INT169053

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0.23

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signal transduction (Oprm1) sulfur compound metabolic process (Sult4a1) plasma membrane (Oprm1)
lipid metabolic process (Sult4a1) cytoplasm (Sult4a1) signal transducer activity (Oprm1)
Oprm1 (Mus musculus)
Sult4a1 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 3 100.00 Very High Very High Very High
Enkephalin 1 85.12 High High
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 1 51.96 Quite High
Schizophrenia 1 45.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that Sult4a1 is a target gene for the mu-opioid receptor signaling pathway and other pathways involving activation of CREB and ATF-2.
mu-opioid receptor Regulation (target) of Sult4a1 associated with opioid receptor
1) Confidence 0.10 Published 2010 Journal Mol. Pharmacol. Section Abstract Doc Link 20571078 Disease Relevance 0.05 Pain Relevance 0.23

General Comments

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