INT169062

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Context Info
Confidence 0.49
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 10
Disease Relevance 3.60
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pnp) extracellular region (Pnp) transferase activity, transferring glycosyl groups (Pnp)
cytoskeleton (Pnp) nucleus (Pnp) intracellular (Pnp)
Anatomy Link Frequency
poly 2
Pnp (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 6 80.64 Quite High
Potency 4 73.80 Quite High
ketamine 7 66.24 Quite High
agonist 50 5.00 Very Low Very Low Very Low
cytokine 26 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
Buprenorphine 10 5.00 Very Low Very Low Very Low
anesthesia 8 5.00 Very Low Very Low Very Low
Pain management 5 5.00 Very Low Very Low Very Low
imagery 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Influenza Virus Infection 122 100.00 Very High Very High Very High
Vesicular Stomatitis 18 100.00 Very High Very High Very High
Neuropathy 6 100.00 Very High Very High Very High
Infection 82 99.96 Very High Very High Very High
Pox Virus Infection 53 99.86 Very High Very High Very High
Diabetes Mellitus 3 98.68 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 9 93.76 High High
Sprains And Strains 41 72.00 Quite High
Lymphopenia 2 71.96 Quite High
Weight Loss 12 71.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In patients with type 2, symptoms of PNP can precede formal diagnosis of diabetes!
Positive_regulation (symptoms) of Gene_expression (symptoms) of PNP associated with neuropathy and diabetes mellitus
1) Confidence 0.49 Published 2010 Journal Praxis (Bern 1994) Section Abstract Doc Link 20571999 Disease Relevance 0.75 Pain Relevance 0.08
Thymidine kinase-negative (TK-) recombinant vaccinia virus expressing influenza A/PR/8/34 NP gene (NP-Vac) was provided by Dr.
Positive_regulation (provided) of Gene_expression (expressing) of NP associated with pox virus infection and influenza virus infection
2) Confidence 0.09 Published 2007 Journal Respir Res Section Body Doc Link PMC1914056 Disease Relevance 0.90 Pain Relevance 0.03
When HA and NP were present, significant humoral responses were stimulated against these proteins.
Positive_regulation (When) of Gene_expression (present) of NP
3) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2843722 Disease Relevance 0.60 Pain Relevance 0
The NP-specific mAb S43-10 (Reth et al., 1978) was used as a positive control for a high-affinity NP-specific IgG2c antibody with an affinities of Kd = 2.4 × 10?
Positive_regulation (control) of Gene_expression (antibody) of NP-specific
4) Confidence 0.03 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2901065 Disease Relevance 0.05 Pain Relevance 0
The NP-specific mAb S43-10 (Reth et al., 1978) was used as a positive control for a high-affinity NP-specific IgG2c antibody with an affinities of Kd = 2.4 × 10?
Positive_regulation (-) of Gene_expression (mAb) of NP-specific
5) Confidence 0.03 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2901065 Disease Relevance 0 Pain Relevance 0
The NP-specific mAb S43-10 (Reth et al., 1978) was used as a positive control for a high-affinity NP-specific IgG2c antibody with an affinities of Kd = 2.4 × 10?
Positive_regulation (-) of Gene_expression (antibody) of NP-specific
6) Confidence 0.03 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2901065 Disease Relevance 0.05 Pain Relevance 0
NP-Ficoll alone elicited Ig?
Positive_regulation (elicited) of Gene_expression (elicited) of NP-Ficoll
7) Confidence 0.03 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2901065 Disease Relevance 0.07 Pain Relevance 0
NP-Ficoll + poly(I:C) induced not only extrafollicular Ig?
Positive_regulation (induced) of Gene_expression (poly) of NP-Ficoll in poly
8) Confidence 0.03 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2901065 Disease Relevance 0.06 Pain Relevance 0
This indicated that a functional TAP complex was formed by the VV-hTAP1,2 infection, leading to high levels of H-2Kb–vesicular stomatitis virus nucleoprotein (VSV-NP) surface expression (Figure 1A).
Positive_regulation (leading) of Gene_expression (expression) of VSV-NP associated with vesicular stomatitis and infection
9) Confidence 0.01 Published 2005 Journal PLoS Pathogens Section Body Doc Link PMC1323471 Disease Relevance 0.57 Pain Relevance 0.06
This indicated that a functional TAP complex was formed by the VV-hTAP1,2 infection, leading to high levels of H-2Kb–vesicular stomatitis virus nucleoprotein (VSV-NP) surface expression (Figure 1A).
Positive_regulation (levels) of Gene_expression (expression) of VSV-NP associated with vesicular stomatitis and infection
10) Confidence 0.01 Published 2005 Journal PLoS Pathogens Section Body Doc Link PMC1323471 Disease Relevance 0.56 Pain Relevance 0.04

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