INT16920

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Context Info
Confidence 0.43
First Reported 1991
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 3.51
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NR0B1) RNA binding (NR0B1) nucleus (NR0B1)
DNA binding (NR0B1) transcription factor binding (NR0B1) response to stress (NR0B1)
Anatomy Link Frequency
null cell 1
NR0B1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Migraine 6 97.44 Very High Very High Very High
Inflammatory response 2 89.60 High High
headache 1 76.52 Quite High
tetrodotoxin 1 72.64 Quite High
Somatostatin 1 29.44 Quite Low
Dopamine 1 27.68 Quite Low
agonist 2 26.96 Quite Low
antagonist 1 25.00 Low Low
Inflammation 4 5.00 Very Low Very Low Very Low
aspirin 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acute Hemorrhagic Conjunctivitis 144 100.00 Very High Very High Very High
Cancer 11 98.44 Very High Very High Very High
Migraine With Aura 5 97.44 Very High Very High Very High
Disease 56 93.00 High High
INFLAMMATION 8 89.24 High High
Neurological Disease 1 87.28 High High
Precocious Puberty 1 87.04 High High
Hemiplegia 3 85.16 High High
Syndrome 1 83.80 Quite High
Hypopituitarism 1 77.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Monday incidence reports (Figure 2) exhibited tremendous increases in AHC case incidence during weekends in Keelung.
Positive_regulation (increases) of AHC associated with acute hemorrhagic conjunctivitis
1) Confidence 0.43 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2776508 Disease Relevance 0.46 Pain Relevance 0
Several characteristics of the 2007 outbreak suggest a foreign source for Taiwan's AHC epidemic.
Positive_regulation (source) of AHC associated with acute hemorrhagic conjunctivitis
2) Confidence 0.31 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2776508 Disease Relevance 0.96 Pain Relevance 0
In addition, the nuclear receptor subfamily 0 (NR0B1) known as a PPAR?
Positive_regulation (receptor) of NR0B1
3) Confidence 0.20 Published 2010 Journal BMC Med Section Body Doc Link PMC2955589 Disease Relevance 0.09 Pain Relevance 0.04
In addition, the nuclear receptor subfamily 0 (NR0B1) known as a PPAR?
Positive_regulation (receptor) of subfamily 0
4) Confidence 0.17 Published 2010 Journal BMC Med Section Body Doc Link PMC2955589 Disease Relevance 0.09 Pain Relevance 0.04
We provide the first evidence that a CACNA1A mutation can cause atypical AHC, indicating an overlap of molecular mechanisms causing AHC and FHM.
Positive_regulation (cause) of AHC associated with migraine
5) Confidence 0.16 Published 2008 Journal Cephalalgia Section Abstract Doc Link 18498393 Disease Relevance 0.77 Pain Relevance 0.53
The tumors can be divided into two broad categories: functioning gonadotropinomas with positive immunostaining for follicle-stimulating hormone, leutinizing hormone, and/or their subunits; and nonfunctioning gonadotropinomas or null cell tumors with negative immunostaining for all pituitary hormones but positive nuclear immunostaining for steroid factor-1 or DAX-1 characteristic of gonadotrope differentiation, with evidence of gonadotropin production or gene expression at the mRNA level.
Positive_regulation (immunostaining) of DAX-1 in null cell associated with cancer
6) Confidence 0.05 Published 2002 Journal Semin. Reprod. Med. Section Abstract Doc Link 12536357 Disease Relevance 1.14 Pain Relevance 0.08
I0(IL-1) was decreased by depolarization and increased by hyperpolarization.
Positive_regulation (increased) of I0
7) Confidence 0.01 Published 1991 Journal Brain Res. Section Abstract Doc Link 1860049 Disease Relevance 0 Pain Relevance 0.07

General Comments

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