INT169212

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Context Info
Confidence 0.28
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.87
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Coc (Mus musculus)
Pain Link Frequency Relevance Heat
cocaine 16 100.00 Very High Very High Very High
Morphine 1 54.20 Quite High
Disease Link Frequency Relevance Heat
Death 2 98.64 Very High Very High Very High
Drug Induced Neurotoxicity 3 97.52 Very High Very High Very High
Necrosis 1 97.44 Very High Very High Very High
Attention Deficit Hyperactivity Disorder 1 88.56 High High
Apoptosis 2 88.24 High High
Parkinson's Disease 1 78.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The data show that drug combinations potentiate cortical neurotoxicity and that the mode of co-exposure changes cellular death pathways activated by the drugs, strongly suggesting that chemical interactions occurring in Her:Coc, such as adduct formation, shift cell death mechanisms towards necrosis.
Positive_regulation (occurring) of Coc Binding (interactions) of associated with necrosis, drug induced neurotoxicity, death and cocaine
1) Confidence 0.28 Published 2010 Journal Toxicology Section Abstract Doc Link 20600547 Disease Relevance 0.87 Pain Relevance 0.58

General Comments

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