INT169216

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Context Info
Confidence 0.42
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.82
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CYCS) transport (CYCS) mitochondrion (CYCS)
small molecule metabolic process (CYCS) nucleus (CYCS)
Anatomy Link Frequency
neuronal 2
CYCS (Homo sapiens)
Pain Link Frequency Relevance Heat
cocaine 16 96.80 Very High Very High Very High
Morphine 1 68.48 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 2 100.00 Very High Very High Very High
Parkinson's Disease 1 93.00 High High
Drug Induced Neurotoxicity 3 88.64 High High
Death 2 83.52 Quite High
Necrosis 1 69.92 Quite High
Attention Deficit Hyperactivity Disorder 1 63.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Conversely, a major increase in cytochrome c release, caspase 3-dependent apoptosis, and decreased metabolic neuronal viability were observed upon sequential exposure to Her and Coc.
Negative_regulation (decreased) of Positive_regulation (increase) of cytochrome c in neuronal associated with apoptosis and cocaine
1) Confidence 0.42 Published 2010 Journal Toxicology Section Abstract Doc Link 20600547 Disease Relevance 0.82 Pain Relevance 0.70

General Comments

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