INT169319

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Context Info
Confidence 0.60
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.31
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell death (Nlrp1a) nucleus (Nlrp1a) enzyme binding (Nlrp1a)
Anatomy Link Frequency
NAc 2
body 2
Nlrp1a (Mus musculus)
Pain Link Frequency Relevance Heat
Nucleus accumbens 27 100.00 Very High Very High Very High
cocaine 70 99.98 Very High Very High Very High
amygdala 6 99.60 Very High Very High Very High
Hippocampus 5 99.08 Very High Very High Very High
Neurotransmitter 2 98.16 Very High Very High Very High
Glutamate 1 97.12 Very High Very High Very High
Opioid 2 95.76 Very High Very High Very High
antagonist 1 95.44 Very High Very High Very High
fluoxetine 1 85.48 High High
Serotonin 3 80.92 Quite High
Disease Link Frequency Relevance Heat
Depression 4 91.52 High High
Drug Dependence 3 43.48 Quite Low
Urological Neuroanatomy 7 16.96 Low Low
Cocaine Dependence 14 11.32 Low Low
Recurrence 4 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Diabetes Mellitus 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Combined, our data argue that control of NAc D2r expression is critical for Rxrgamma-mediated modulation of affective behaviors.
Regulation (control) of Gene_expression (expression) of NAc in NAc associated with nucleus accumbens
1) Confidence 0.60 Published 2010 Journal Neuron Section Abstract Doc Link 20620876 Disease Relevance 0.31 Pain Relevance 0.50
Cocaine affects the expression of numerous genes within the NAc, including some that influence the important neurotransmitter chemical glutamate and the brain’s natural opioid-like compounds produced by the body (Kalivas and McFarland, 2003; Nestler, 2001).
Regulation (affects) of Gene_expression (expression) of NAc in body associated with nucleus accumbens, glutamate, neurotransmitter, opioid and cocaine
2) Confidence 0.06 Published 2005 Journal Sci Pract Perspect Section Body Doc Link PMC2851032 Disease Relevance 0 Pain Relevance 0.50

General Comments

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