INT169387

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.36
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.19
Pain Relevance 1.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Chrna7) plasma membrane (Chrna7) cytoplasm (Chrna7)
Anatomy Link Frequency
muscles 2
Chrna7 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Botox 33 97.24 Very High Very High Very High
Spinal cord 1 96.76 Very High Very High Very High
Pain 16 96.32 Very High Very High Very High
tetrodotoxin 1 95.44 Very High Very High Very High
GABAergic 5 95.36 Very High Very High Very High
Piles 23 91.04 High High
agonist 1 88.24 High High
antagonist 3 87.36 High High
Angina 7 81.28 Quite High
Analgesic 1 81.04 Quite High
Disease Link Frequency Relevance Heat
Pain 16 98.36 Very High Very High Very High
Muscular Spasm 4 97.52 Very High Very High Very High
Dysphagia 34 95.52 Very High Very High Very High
Anorectal Disorders 25 91.04 High High
Disease 5 85.28 High High
Angina 7 81.28 Quite High
Skin Appendage Disease 7 79.96 Quite High
Clostridium Infection 2 78.32 Quite High
Syndrome 1 77.48 Quite High
Acid Reflux 5 77.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, sphincter manometry after BTX injection has demonstrated a lowering of resting intranal pressure.[6]

SELECTION OF PATIENTS

Regulation (after) of Gene_expression (injection) of BTX
1) Confidence 0.36 Published 2008 Journal Journal of Cutaneous and Aesthetic Surgery Section Body Doc Link PMC2840903 Disease Relevance 0.91 Pain Relevance 0.29
On the other hand, BTX injection into muscles has indirect effects on CNS activity.[1617]

BTX: EFFECTS ON PAIN

Regulation (effects) of Gene_expression (injection) of BTX in muscles associated with pain
2) Confidence 0.33 Published 2008 Journal Journal of Cutaneous and Aesthetic Surgery Section Body Doc Link PMC2840887 Disease Relevance 0.71 Pain Relevance 0.82
Disruption of the cytoskeleton affected alpha7-nAChR mobility and cell surface expression, but not their ability to form clusters.
Regulation (affected) of Gene_expression (expression) of alpha7-nAChR
3) Confidence 0.27 Published 2010 Journal PLoS ONE Section Abstract Doc Link 20634896 Disease Relevance 0.05 Pain Relevance 0.37
There was no significant difference in the clinical response to BTX injection among patients (n = 14) who had received treatment prior to the study, in comparison with previously untreated achalasia patients who received BTX as the first treatment (n = 26) (table 2).
Regulation (response) of Gene_expression (injection) of BTX associated with dysphagia
4) Confidence 0.22 Published 2002 Journal BMC Gastroenterol Section Body Doc Link PMC122056 Disease Relevance 0.52 Pain Relevance 0.14

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox