INT169405

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IGF1) extracellular space (IGF1) extracellular region (IGF1)
IGF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 3 94.08 High High
Enkephalin 1 81.28 Quite High
agonist 1 79.52 Quite High
MU agonist 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Neuroblastoma 2 77.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Silencing of beta-arrestin 2 uncouples the crosstalk between the two receptors, thus maintaining IGF-I-mediated receptor phosphorylation and ERK 1/2 activation even after prolonged DAMGO exposure.
Negative_regulation (maintaining) of Phosphorylation (phosphorylation) of IGF-I-mediated
1) Confidence 0.07 Published 2010 Journal FEBS Lett. Section Abstract Doc Link 20643133 Disease Relevance 0.15 Pain Relevance 0.32

General Comments

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