INT169421

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.49
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 6
Disease Relevance 2.42
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (FOXC1) nucleus (FOXC1) DNA binding (FOXC1)
transcription factor binding (FOXC1) cytoplasm (FOXC1)
Anatomy Link Frequency
enterocytes 1
CSF 1
FOXC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
methotrexate 1 98.48 Very High Very High Very High
Inflammation 102 97.96 Very High Very High Very High
intrathecal 2 97.24 Very High Very High Very High
cytokine 120 87.40 High High
backache 1 85.44 High High
Inflammatory response 6 78.80 Quite High
dexamethasone 21 72.40 Quite High
agonist 36 66.64 Quite High
cerebral cortex 20 64.16 Quite High
chemokine 6 46.00 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 105 97.96 Very High Very High Very High
Inflammatory Bowel Disease 96 93.92 High High
Adhesions 6 93.92 High High
Cranial Neuropathy 2 86.36 High High
Low Back Pain 1 85.44 High High
Meningitis 3 84.56 Quite High
Lymphatic System Cancer 1 83.16 Quite High
Skin Cancer 1 82.40 Quite High
Lung Cancer 1 82.00 Quite High
Breast Cancer 1 81.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Liposomal Ara-C is distributed over the entire CSF space even after lumbar application and maintains cytotoxic levels for at least 2 weeks.
Positive_regulation (distributed) of Ara in CSF
1) Confidence 0.49 Published 2010 Journal Expert Rev Anticancer Ther Section Abstract Doc Link 20645702 Disease Relevance 1.05 Pain Relevance 0.22
Thus, the hypothesis that ARA-supplemented formula always increases CNS ARA is rejected.
Positive_regulation (increases) of CNS ARA
2) Confidence 0.40 Published 2005 Journal BMC Med Section Body Doc Link PMC1184078 Disease Relevance 0 Pain Relevance 0
Our treatments are a strong test of the hypothesis that LCP supplementation increases CNS LCP concentrations for DHA and ARA, the two LCP that have garnered the most attention for the developing human infant CNS.
Positive_regulation (concentrations) of ARA
3) Confidence 0.29 Published 2005 Journal BMC Med Section Body Doc Link PMC1184078 Disease Relevance 0 Pain Relevance 0.03
B activation of ARA and EPA.
Positive_regulation (activation) of ARA
4) Confidence 0.11 Published 2007 Journal Lipids Section Body Doc Link PMC2039812 Disease Relevance 0.27 Pain Relevance 0.13
Moreover, colonic arachidonic acid (ARA) proportions are increased and oleic acid (OA) proportions are decreased.
Positive_regulation (increased) of ARA
5) Confidence 0.07 Published 2007 Journal Lipids Section Abstract Doc Link PMC2039812 Disease Relevance 0.47 Pain Relevance 0.19
Because EPA and OA resulted in comparable changes in the proportions of ARA in the phospholipids of the enterocytes, the reported effects may be ascribed to the increased ARA proportion in the ARA cultured cells.
Positive_regulation (increased) of ARA in enterocytes
6) Confidence 0.07 Published 2007 Journal Lipids Section Body Doc Link PMC2039812 Disease Relevance 0.63 Pain Relevance 0.12

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox