INT169441

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.70
Pain Relevance 1.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (TAC1, Tac1) extracellular region (TAC1, Tac1) plasma membrane (TAC1, Tac1)
cell-cell signaling (TAC1)
Anatomy Link Frequency
neurons 2
TAC1 (Homo sapiens)
Tac1 (Mus musculus)
Pain Link Frequency Relevance Heat
substance P 14 100.00 Very High Very High Very High
Inflammation 6 100.00 Very High Very High Very High
Peripheral sensitization 2 92.68 High High
nociceptor 6 90.28 High High
imagery 2 89.60 High High
Stimulus evoked pain 2 87.00 High High
agonist 2 80.32 Quite High
antagonist 2 65.04 Quite High
Pain 2 51.76 Quite High
adenocard 2 46.40 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 6 100.00 Very High Very High Very High
Nociception 8 99.42 Very High Very High Very High
Hypersensitivity 2 87.00 High High
Pain 4 86.32 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, we investigated whether P2X3 activity in trigeminal nociceptive neurons is regulated by the neurokinin-1 (NK-1) receptor that is activated by an inflammatory mediator, substance P.
substance P Positive_regulation (activated) of neurokinin-1 in neurons associated with nociception, inflammation and substance p
1) Confidence 0.01 Published 2010 Journal J. Dent. Res. Section Abstract Doc Link 20651096 Disease Relevance 0.85 Pain Relevance 0.82
Thus, we investigated whether P2X3 activity in trigeminal nociceptive neurons is regulated by the neurokinin-1 (NK-1) receptor that is activated by an inflammatory mediator, substance P.
substance P Positive_regulation (activated) of NK-1 in neurons associated with nociception, inflammation and substance p
2) Confidence 0.01 Published 2010 Journal J. Dent. Res. Section Abstract Doc Link 20651096 Disease Relevance 0.85 Pain Relevance 0.82

General Comments

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