INT169464

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Context Info
Confidence 0.28
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.63
Pain Relevance 1.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Akt1, Egfr) plasma membrane (Akt1, Egfr) translation (Akt1, Egfr)
enzyme binding (Akt1, Egfr) cytoplasm (Akt1, Egfr) signal transduction (Akt1, Egfr)
Akt1 (Mus musculus)
Egfr (Mus musculus)
Pain Link Frequency Relevance Heat
qutenza 24 98.92 Very High Very High Very High
COX2 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Targeted Disruption 14 99.28 Very High Very High Very High
Cancer 4 82.60 Quite High
Skin Cancer 2 77.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TPA/capsaicin cotreatment caused EGFR tyrosine phosphorylation and activated EGFR downstream signaling, including ERKs and Akt in EGFR/WT, but not EGFR/KO cells.
Akt Positive_regulation (activated) of EGFR associated with targeted disruption and qutenza
1) Confidence 0.28 Published 2010 Journal Cancer Res. Section Abstract Doc Link 20660715 Disease Relevance 0.81 Pain Relevance 0.85
TPA/capsaicin cotreatment caused EGFR tyrosine phosphorylation and activated EGFR downstream signaling, including ERKs and Akt in EGFR/WT, but not EGFR/KO cells.
Akt Positive_regulation (activated) of EGFR associated with targeted disruption and qutenza
2) Confidence 0.13 Published 2010 Journal Cancer Res. Section Abstract Doc Link 20660715 Disease Relevance 0.81 Pain Relevance 0.85

General Comments

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