INT169468

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 4
Disease Relevance 3.73
Pain Relevance 1.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Egfr) cell morphogenesis (Egfr) Golgi apparatus (Egfr)
endoplasmic reticulum (Egfr) intracellular (Egfr) enzyme binding (Egfr)
Egfr (Mus musculus)
Spink3 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 4 95.08 Very High Very High Very High
Chronic pancreatitis 20 93.36 High High
Disease Link Frequency Relevance Heat
Fibrosis 4 95.08 Very High Very High Very High
Frailty 4 94.68 High High
Adenocarcinoma 20 94.60 High High
Pancreatitis 20 93.36 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, expression of epidermal growth factor receptor (EGFR) and its ligands; serine protease inhibitor Kazal type 3 (Spink3) and transforming growth factor alpha (TGF alpha) and activation of K-Ras (GTP-Ras formation), which are frequently observed in human PDA, were indeed observed in parallel with TCs formation.
epidermal growth factor receptor Binding (ligands) of Spink3 associated with adenocarcinoma
1) Confidence 0.37 Published 2010 Journal Exp. Anim. Section Abstract Doc Link 20660988 Disease Relevance 0.94 Pain Relevance 0.46
Furthermore, expression of epidermal growth factor receptor (EGFR) and its ligands; serine protease inhibitor Kazal type 3 (Spink3) and transforming growth factor alpha (TGF alpha) and activation of K-Ras (GTP-Ras formation), which are frequently observed in human PDA, were indeed observed in parallel with TCs formation.
EGFR Binding (ligands) of Spink3 associated with adenocarcinoma
2) Confidence 0.37 Published 2010 Journal Exp. Anim. Section Abstract Doc Link 20660988 Disease Relevance 0.93 Pain Relevance 0.45
Furthermore, expression of epidermal growth factor receptor (EGFR) and its ligands; serine protease inhibitor Kazal type 3 (Spink3) and transforming growth factor alpha (TGF alpha) and activation of K-Ras (GTP-Ras formation), which are frequently observed in human PDA, were indeed observed in parallel with TCs formation.
EGFR Binding (ligands) of serine protease inhibitor Kazal type 3 associated with adenocarcinoma
3) Confidence 0.37 Published 2010 Journal Exp. Anim. Section Abstract Doc Link 20660988 Disease Relevance 0.93 Pain Relevance 0.45
Furthermore, expression of epidermal growth factor receptor (EGFR) and its ligands; serine protease inhibitor Kazal type 3 (Spink3) and transforming growth factor alpha (TGF alpha) and activation of K-Ras (GTP-Ras formation), which are frequently observed in human PDA, were indeed observed in parallel with TCs formation.
epidermal growth factor receptor Binding (ligands) of serine protease inhibitor Kazal type 3 associated with adenocarcinoma
4) Confidence 0.37 Published 2010 Journal Exp. Anim. Section Abstract Doc Link 20660988 Disease Relevance 0.94 Pain Relevance 0.46

General Comments

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