INT169474

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Context Info
Confidence 0.73
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.12
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (MTG1) nucleolus (MTG1) nucleus (MTG1)
MTG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 1 87.92 High High
Chronic pancreatitis 5 86.20 High High
imagery 5 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Congenital analgesia 1 5.00 Very Low Very Low Very Low
Demyelination 1 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
Peripheral nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adenocarcinoma 5 99.60 Very High Very High Very High
Disease 76 93.28 High High
Fibrosis 1 87.92 High High
Frailty 1 87.52 High High
Pancreatitis 5 86.20 High High
Charcot Marie Tooth Disease 6 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Neurological Disease 2 5.00 Very Low Very Low Very Low
Syndrome 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, expression of epidermal growth factor receptor (EGFR) and its ligands; serine protease inhibitor Kazal type 3 (Spink3) and transforming growth factor alpha (TGF alpha) and activation of K-Ras (GTP-Ras formation), which are frequently observed in human PDA, were indeed observed in parallel with TCs formation.
Localization (observed) of GTP associated with adenocarcinoma
1) Confidence 0.73 Published 2010 Journal Exp. Anim. Section Abstract Doc Link 20660988 Disease Relevance 0.88 Pain Relevance 0.43
As expected, wild-type Rab7 showed a slow rate of GTP exchange in the absence of GEF activity (only 10–20% of maximal binding).
Localization (rate) of GTP
2) Confidence 0.03 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2830827 Disease Relevance 0.24 Pain Relevance 0

General Comments

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