INT169477

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.83
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (TGFB3, Spink3) extracellular space (TGFB3) aging (TGFB3)
plasma membrane (TGFB3) nucleus (TGFB3) embryo development (TGFB3)
TGFB3 (Homo sapiens)
Spink3 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 2 92.80 High High
Chronic pancreatitis 10 91.08 High High
Disease Link Frequency Relevance Heat
Adenocarcinoma 10 97.20 Very High Very High Very High
Fibrosis 2 92.80 High High
Frailty 2 92.40 High High
Pancreatitis 10 91.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, expression of epidermal growth factor receptor (EGFR) and its ligands; serine protease inhibitor Kazal type 3 (Spink3) and transforming growth factor alpha (TGF alpha) and activation of K-Ras (GTP-Ras formation), which are frequently observed in human PDA, were indeed observed in parallel with TCs formation.
TGF alpha Positive_regulation (activation) of serine protease inhibitor Kazal type 3 associated with adenocarcinoma
1) Confidence 0.02 Published 2010 Journal Exp. Anim. Section Abstract Doc Link 20660988 Disease Relevance 0.92 Pain Relevance 0.45
Furthermore, expression of epidermal growth factor receptor (EGFR) and its ligands; serine protease inhibitor Kazal type 3 (Spink3) and transforming growth factor alpha (TGF alpha) and activation of K-Ras (GTP-Ras formation), which are frequently observed in human PDA, were indeed observed in parallel with TCs formation.
TGF alpha Positive_regulation (activation) of Spink3 associated with adenocarcinoma
2) Confidence 0.02 Published 2010 Journal Exp. Anim. Section Abstract Doc Link 20660988 Disease Relevance 0.91 Pain Relevance 0.44

General Comments

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