INT169484

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Dbi, Oprk1) transport (Dbi) mitochondrion (Dbi)
signal transducer activity (Oprk1) cytoplasm (Dbi) lipid binding (Dbi)
Dbi (Rattus norvegicus)
Oprk1 (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 4 50.00 Quite Low
tolerance 4 50.00 Quite Low
Kappa opioid receptor 4 50.00 Quite Low
Analgesic 3 50.00 Quite Low
Kinase C 2 50.00 Quite Low
Pain 3 10.00 Low Low
Lasting pain 2 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 2 66.72 Quite High
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, AS-ODN targeting KOR significantly reversed the chronic pain-induced down-regulation of PKC activity or up-regulation of MOR [(35)S]GTPgammaS binding activity after repeated morphine treatment.
AS-ODN Regulation (targeting) of KOR
1) Confidence 0.01 Published 2010 Journal J. Pharm. Pharmacol. Section Body Doc Link 20663033 Disease Relevance 0.07 Pain Relevance 0

General Comments

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