INT16960

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Context Info
Confidence 0.76
First Reported 1983
Last Reported 2010
Negated 7
Speculated 7
Reported most in Abstract
Documents 166
Total Number 173
Disease Relevance 116.21
Pain Relevance 34.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Crp) extracellular region (Crp)
Anatomy Link Frequency
erythrocyte 18
plasma 12
coronary artery 8
blood 7
leukocyte 5
Crp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 514 100.00 Very High Very High Very High
cytokine 136 100.00 Very High Very High Very High
Pain 136 100.00 Very High Very High Very High
methotrexate 65 100.00 Very High Very High Very High
Pain score 3 99.92 Very High Very High Very High
Inflammatory marker 156 99.82 Very High Very High Very High
Angina 293 99.72 Very High Very High Very High
imagery 40 99.60 Very High Very High Very High
rheumatoid arthritis 122 99.28 Very High Very High Very High
Ultiva 1 99.02 Very High Very High Very High
Disease Link Frequency Relevance Heat
INFLAMMATION 704 100.00 Very High Very High Very High
Disease 297 100.00 Very High Very High Very High
Coronary Artery Disease 226 100.00 Very High Very High Very High
Pain 114 100.00 Very High Very High Very High
Cancer 80 100.00 Very High Very High Very High
Insulin Resistance 62 100.00 Very High Very High Very High
Necrosis 29 100.00 Very High Very High Very High
Alzheimer's Dementia 17 100.00 Very High Very High Very High
Carcinoma 2 100.00 Very High Very High Very High
Nicotine Addiction 408 99.98 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hypochromic anemia, hypergammaglobulinemia, and elevated C-reactive protein were found in this case.
Gene_expression (found) of C-reactive protein associated with hypergammaglobulinemia and hypochromic anemia
1) Confidence 0.76 Published 2002 Journal Surg. Today Section Abstract Doc Link 12111527 Disease Relevance 0.71 Pain Relevance 0.15
Increased levels of C-reactive protein, erythrocyte sedimentation rate and procalcitonin were detected in 88%, 94% and 42% of the patients, respectively.
Gene_expression (levels) of C-reactive protein in erythrocyte
2) Confidence 0.76 Published 2008 Journal Mikrobiyol Bul Section Abstract Doc Link 18697423 Disease Relevance 1.16 Pain Relevance 0.09
Details of diets, smoking habits, medication used, body mass index, and the presence of hypertension and diabetes were recorded, as were plasma lipid and glucose levels, C-reactive protein, and lipoperoxidation in all participants.
Gene_expression (recorded) of C-reactive protein in plasma
3) Confidence 0.66 Published 2002 Journal Arq. Bras. Cardiol. Section Body Doc Link 12219190 Disease Relevance 0.17 Pain Relevance 0
MAIN OUTCOME MEASURES: Body mass index; levels of C-reactive protein, homocysteine, serum and red blood cell folate, vitamin B(12), methylmalonic acid, total cholesterol, high-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, triglycerides, and uric acid; and platelet count.
Gene_expression (levels) of C-reactive protein in platelet
4) Confidence 0.66 Published 2010 Journal Arch Pediatr Adolesc Med Section Body Doc Link 20368489 Disease Relevance 0.16 Pain Relevance 0
Effect of nifedipine on C-reactive protein levels in the coronary sinus and on coronary blood flow in response to acetylcholine in patients with stable angina pectoris having percutaneous coronary intervention.
Gene_expression (levels) of C-reactive protein in coronary sinus associated with stable angina pectoris and angina
5) Confidence 0.66 Published 2005 Journal Am. J. Cardiol. Section Title Doc Link 15877999 Disease Relevance 0.28 Pain Relevance 0.27
The raised erythrocyte sedimentation rate and C-reactive protein levels were found in 63% and 80%, respectively.
Gene_expression (levels) of C-reactive protein in erythrocyte
6) Confidence 0.66 Published 2009 Journal Clin. Rheumatol. Section Abstract Doc Link 18797980 Disease Relevance 1.54 Pain Relevance 0.09
There were significant differences in the incidences of fever (p = 0.004) and rebound tenderness (p = 0.019), and in white cell counts (p < 0.001), neutrophil percentages (p < 0.001), and C-reactive protein levels (p < 0.001) between patients with appendicitis and patients with other causes of RLQ pain.
Gene_expression (levels) of C-reactive protein in neutrophil associated with appendicitis, pain and fever
7) Confidence 0.66 Published 2009 Journal Kaohsiung J. Med. Sci. Section Abstract Doc Link 19289311 Disease Relevance 1.65 Pain Relevance 0.55
C-reactive protein was present in 22 cases (33.84%), 9 of which were associated with recurrent events (34.61%) vs 13 which were free of them (odds ratio, p = 0.5).
Gene_expression (present) of reactive protein
8) Confidence 0.65 Published 1997 Journal Arch Inst Cardiol Mex Section Body Doc Link 9585827 Disease Relevance 0.30 Pain Relevance 0
There weren’t significant differences in the levels of prostaglandin E2 (PGE2), triglycerides, cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), LDL/HDL, cholesterol/HDL, fasting blood sugar, C-reactive protein (CRP), arylestrase activity, platelet count and body mass index between groups.
Gene_expression (activity) of C-reactive protein in blood associated with obesity and disorder of lipid metabolism
9) Confidence 0.65 Published 2008 Journal Vascular Health and Risk Management Section Abstract Doc Link PMC2663461 Disease Relevance 0.66 Pain Relevance 0.13
hsCRP – highly sensitive C-reactive protein
Gene_expression (sensitive) of CRP
10) Confidence 0.65 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC1079905 Disease Relevance 2.02 Pain Relevance 0
Forearm blood flow after reactive hyperemia response (FBF(h) ) or oral nitroglycerine spray to evaluate endothelial-dependent and endothelial-independent vasodilation, respectively, pain-free and maximal walking distance, levels of C-reactive protein, triglycerides, cholesterol, low-density lipoprotein, and high-density lipoprotein-cholesterol in plasma were determined.
Gene_expression (levels) of C-reactive protein in plasma associated with pain, hyperemia and increased venous pressure under development
11) Confidence 0.62 Published 2008 Journal Angiology Section Abstract Doc Link 18388031 Disease Relevance 0.99 Pain Relevance 0.38
Surprisingly, these mediators, which include complement proteins, inflammatory cytokines, prostaglandins, and acute phase reactants such as C-reactive protein and amyloid P, are produced by resident brain cells, including neurons.
Gene_expression (produced) of C-reactive protein in neurons associated with inflammation, alzheimer's dementia and cytokine
12) Confidence 0.59 Published 2002 Journal Sci Aging Knowledge Environ Section Abstract Doc Link 14602998 Disease Relevance 0.99 Pain Relevance 0.26
Levels of C-reactive protein or erythrocyte sedimentation rates were elevated in all cases, usually to levels found in serious bacterial diseases.
Gene_expression (Levels) of C-reactive protein in erythrocyte associated with bacterial infection
13) Confidence 0.59 Published 1989 Journal Rev. Infect. Dis. Section Abstract Doc Link 2574903 Disease Relevance 1.93 Pain Relevance 0.32
Plasma levels of C-reactive protein were measured 72 hours after successful coronary artery stenting in 76 patients with stable angina pectoris.
Gene_expression (levels) of C-reactive protein in coronary artery associated with stable angina pectoris and angina
14) Confidence 0.59 Published 1998 Journal Am. J. Cardiol. Section Abstract Doc Link 9723643 Disease Relevance 0.17 Pain Relevance 0.17
At that time, the C-reactive protein was negative and the histopathologic findings of the specimens of the aorta could not confirm aortitis.
Neg (negative) Gene_expression (negative) of C-reactive protein in aorta associated with aortitis
15) Confidence 0.59 Published 1993 Journal Angiology Section Abstract Doc Link 8105733 Disease Relevance 0.82 Pain Relevance 0.13
Levels of high-sensitivity C-reactive protein decreased after treatment with antispastic agents.
Gene_expression (Levels) of C-reactive protein
16) Confidence 0.59 Published 2005 Journal Am. J. Cardiol. Section Abstract Doc Link 15619396 Disease Relevance 0.15 Pain Relevance 0.26
Our results suggest that in patients with unstable angina and 1-vessel coronary disease successfully treated with coronary artery stent implantation, normal baseline serum levels of C-reactive protein identify a subgroup of patients at low risk of cardiac events during follow-up.
Gene_expression (levels) of C-reactive protein in coronary artery associated with angina and coronary heart disease
17) Confidence 0.59 Published 2000 Journal Am. J. Cardiol. Section Abstract Doc Link 11078243 Disease Relevance 0.44 Pain Relevance 0.34
This article examines the effects of elk velvet antler on joint pain and swelling, patient/physician global assessment of disease activity, functional ability, quality of life, blood levels of C-reactive protein, and adverse events in persons with stage 2 to 3 rheumatoid arthritis experiencing residual symptoms after standard treatment.
Gene_expression (levels) of C-reactive protein in joint associated with pain, pressure and volume under development, arthralgia, rheumatoid arthritis and disease
18) Confidence 0.59 Published 2008 Journal Biol Res Nurs Section Abstract Doc Link 18077778 Disease Relevance 0.55 Pain Relevance 0.22
Serum C-reactive protein levels were normal in seven out of 10 cases.
Gene_expression (levels) of C-reactive protein
19) Confidence 0.58 Published 2009 Journal Chir Organi Mov Section Abstract Doc Link 19711173 Disease Relevance 0.70 Pain Relevance 0.29
The Cox proportional hazards model adjusting for coronary risk factors, ACS presentation, extent of coronary artery disease, C-reactive protein and other covariates identified leucocyte count with a HR (hazard ratio)=1.05 (95% CI 1.02-1.07; P<0.001 for 1000 cells/mm(3) increase in the leucocyte count), but not C-reactive protein (HR=1.13, 95% CI 0.95-1.34; P=0.15 for a 1 tertile increase in the C-reactive protein concentration) as an independent correlate of 1-year mortality.
Gene_expression (adjusting) of C-reactive protein in coronary artery associated with coronary artery disease
20) Confidence 0.58 Published 2009 Journal Clin. Sci. Section Abstract Doc Link 18851714 Disease Relevance 0.38 Pain Relevance 0.08

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