INT169603

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Context Info
Confidence 0.26
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.95
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Nppb) extracellular region (Nppb) plasma membrane (Npr1)
intracellular (Npr1) nucleus (Nppb) cytoplasm (Nppb)
Anatomy Link Frequency
afferent neurons 1
Nppb (Rattus norvegicus)
Npr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Thermal hyperalgesia 2 99.68 Very High Very High Very High
IPN 2 95.00 High High
intrathecal 1 80.92 Quite High
Glutamate 1 76.80 Quite High
dorsal root ganglion 3 75.32 Quite High
Calcitonin gene-related peptide 3 72.08 Quite High
Pain 4 55.52 Quite High
fibrosis 1 49.28 Quite Low
Inflammation 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Nociception 3 100.00 Very High Very High Very High
Hyperalgesia 2 99.68 Very High Very High Very High
Inflammatory Pain 2 95.00 High High
Ganglion Cysts 3 75.32 Quite High
Natriuresis 3 75.00 Quite High
Pain 1 55.52 Quite High
Fibrosis 1 49.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, BNP negatively regulates nociceptive transmission through presynaptic receptor NPR-A, and activation of the BNP/NPR-A/PKG/BKCa channel pathway in nociceptive afferent neurons could be a potential strategy for inflammatory pain therapy.
BNP Regulation (regulates) of NPR-A in afferent neurons associated with nociception and ipn
1) Confidence 0.26 Published 2010 Journal J. Neurosci. Section Abstract Doc Link 20702721 Disease Relevance 0.95 Pain Relevance 0.69

General Comments

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