INT169611

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Context Info
Confidence 0.24
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (RAN, OGFR) nucleus (RAN, OGFR) nucleoplasm (RAN)
GTPase activity (RAN) cytosol (RAN) signal transduction (RAN)
Anatomy Link Frequency
nucleus 1
RAN (Homo sapiens)
OGFR (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 1 80.32 Quite High
Opioid 2 78.72 Quite High
Disease Link Frequency Relevance Heat
Skin Cancer 2 96.40 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This study determined the specific transport factors required for the import of the OGF-OGFr complex from the cytoplasm to the nucleus using a probe of full-length OGFr fused to enhanced green fluorescent protein (eGFP) and knockdown of karyopherin alpha1, alpha2, alpha3, alpha4 or alpha6, karyopherin beta1 or Ran with small interfering RNA (siRNA).
Ran Binding (knockdown) of OGFr in nucleus
1) Confidence 0.24 Published 2010 Journal Exp. Biol. Med. (Maywood) Section Abstract Doc Link 20705629 Disease Relevance 0.19 Pain Relevance 0.23

General Comments

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