INT169654

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Context Info
Confidence 0.49
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.26
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Mgll) lipid metabolic process (Mgll)
Mgll (Mus musculus)
Pain Link Frequency Relevance Heat
Endocannabinoid 23 98.24 Very High Very High Very High
tolerance 2 94.68 High High
Opioid 1 93.24 High High
Cannabinoid 2 92.76 High High
Analgesic 4 88.00 High High
Cannabinoid receptor 12 83.92 Quite High
agonist 5 81.76 Quite High
Physical dependence 1 71.44 Quite High
analgesia 3 49.68 Quite Low
Pain 4 25.00 Low Low
Disease Link Frequency Relevance Heat
Sprains And Strains 28 96.48 Very High Very High Very High
Drug Dependence 1 71.44 Quite High
Pain 2 5.00 Very Low Very Low Very Low
Hypothermia 2 5.00 Very Low Very Low Very Low
Obesity 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 2 5.00 Very Low Very Low Very Low
Appetite Loss 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that a similar form of functional antagonism was produced by sustained inactivation of monoacylglycerol lipase (MAGL), the principal degradative enzyme for the endocannabinoid 2-arachidonoylglycerol.
Positive_regulation (inactivation) of MAGL associated with endocannabinoid
1) Confidence 0.49 Published 2010 Journal Nat. Neurosci. Section Abstract Doc Link 20729846 Disease Relevance 0.07 Pain Relevance 0.66
Next, we introduced murine MGL for heterologous expression into the yju3?
Positive_regulation (murine) of MGL
2) Confidence 0.11 Published 2010 Journal Biochimica et Biophysica Acta Section Body Doc Link PMC2911655 Disease Relevance 0.10 Pain Relevance 0
Next, we introduced murine MGL for heterologous expression into the yju3?
Positive_regulation (introduced) of MGL
3) Confidence 0.11 Published 2010 Journal Biochimica et Biophysica Acta Section Body Doc Link PMC2911655 Disease Relevance 0.10 Pain Relevance 0

General Comments

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