INT169657

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Context Info
Confidence 0.24
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.56
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neutrophils 2
Pbrgcsf1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 20 99.00 Very High Very High Very High
chemokine 8 93.44 High High
imagery 1 90.40 High High
Inflammatory response 4 83.04 Quite High
Inflammation 30 80.52 Quite High
Analgesic 2 40.72 Quite Low
cINOD 4 34.16 Quite Low
Pain 1 25.00 Low Low
COX-2 inhibitor 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Peritonitis 1 99.36 Very High Very High Very High
Emergencies 1 98.40 Very High Very High Very High
Stress 3 97.88 Very High Very High Very High
Infection 35 96.60 Very High Very High Very High
INFLAMMATION 34 83.04 Quite High
Targeted Disruption 7 78.68 Quite High
Candida Infection 1 71.92 Quite High
Influenza Virus Infection 31 50.00 Quite Low
Viral Infection 11 50.00 Quite Low
Disease 4 48.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Significantly impaired levels of G-CSF and GM-CSF and of other cytokines such as TNF?
Negative_regulation (impaired) of Gene_expression (levels) of G-CSF associated with cytokine
1) Confidence 0.24 Published 2010 Journal J. Biol. Chem. Section Abstract Doc Link 20736176 Disease Relevance 0.61 Pain Relevance 0.44
However, the depressed levels of G-CSF in the COX inhibitor treated groups appear not to have significantly affected BAL fluid neutrophil levels; in fact, neutrophils were slightly elevated on day 4 in the celecoxib treated group.
Negative_regulation (inhibitor) of Gene_expression (levels) of G-CSF in neutrophils
2) Confidence 0.20 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2904706 Disease Relevance 0.95 Pain Relevance 0

General Comments

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