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Context Info
Confidence 0.43
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 1.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Creb1) nucleus (Creb1) DNA binding (Creb1)
transcription factor binding (Creb1)
Creb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Locus ceruleus 12 99.96 Very High Very High Very High
Morphine 5 98.80 Very High Very High Very High
opioid receptor 1 89.52 High High
withdrawal 1 86.20 High High
Neuronal excitability 2 85.00 Quite High
opiate 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 1 90.56 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Knockdown of CREB in slice cultures from floxed CREB mice similarly decreased LC excitability.
Negative_regulation (decreased) of Negative_regulation (Knockdown) of CREB associated with locus ceruleus
1) Confidence 0.43 Published 2010 Journal Proc. Natl. Acad. Sci. U.S.A. Section Abstract Doc Link 20837544 Disease Relevance 0.09 Pain Relevance 1.22

General Comments

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