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Context Info
Confidence 0.57
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.57
Pain Relevance 0.73

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cell differentiation (HIF1A) signal transduction (HIF1A) nucleolus (HIF1A)
nucleus (HIF1A) transcription factor binding (HIF1A) cytoplasm (HIF1A)
HIF1A (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 7 99.26 Very High Very High Very High
Inflammation 2 90.96 High High
Opioid 1 82.04 Quite High
Disease Link Frequency Relevance Heat
Hypoxia 1 94.72 High High
INFLAMMATION 2 90.96 High High
Wound Healing 3 85.84 High High
Injury 1 67.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Morphine treatment resulted in a significant decrease in the expression and nuclear translocation of HIF-1 alpha with a concurrent suppression in vascular endothelial growth factor (VEGF) synthesis.
Negative_regulation (decrease) of Localization (translocation) of HIF-1 alpha associated with morphine
1) Confidence 0.57 Published 2010 Journal Cell. Immunol. Section Abstract Doc Link 20843508 Disease Relevance 0.57 Pain Relevance 0.73

General Comments

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