INT169764

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Context Info
Confidence 0.56
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Mir16-1 (Mus musculus)
Pain Link Frequency Relevance Heat
fluoxetine 2 99.80 Very High Very High Very High
sSRI 4 99.58 Very High Very High Very High
Raphe 2 99.04 Very High Very High Very High
antidepressant 3 89.16 High High
Serotonin 3 85.20 High High
Locus ceruleus 1 85.12 High High
monoamine 1 64.72 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In mice, chronic treatment with the SSRI fluoxetine (Prozac) increases miR-16 levels in serotonergic raphe nuclei, which reduces SERT expression.
Positive_regulation (increases) of miR-16 associated with raphe, ssri and fluoxetine
1) Confidence 0.56 Published 2010 Journal Science Section Abstract Doc Link 20847275 Disease Relevance 0 Pain Relevance 0.77

General Comments

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