INT169767

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Context Info
Confidence 0.38
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neurons 2
Mir16-1 (Mus musculus)
Pain Link Frequency Relevance Heat
antidepressant 3 97.72 Very High Very High Very High
sSRI 4 97.04 Very High Very High Very High
fluoxetine 2 94.64 High High
Serotonin 3 93.76 High High
Raphe 2 89.84 High High
Locus ceruleus 1 76.88 Quite High
monoamine 1 56.48 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We show that SERT is a target of microRNA-16 (miR-16). miR-16 is expressed at higher levels in noradrenergic than in serotonergic cells; its reduction in noradrenergic neurons causes de novo SERT expression.
Positive_regulation (causes) of Gene_expression (expressed) of miR-16 in neurons
1) Confidence 0.38 Published 2010 Journal Science Section Abstract Doc Link 20847275 Disease Relevance 0 Pain Relevance 0.75

General Comments

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