INT169787

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Context Info
Confidence 0.32
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.77
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Ptger3)
Anatomy Link Frequency
duodenum 3
stomach 1
Ptger3 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 4 90.80 High High
qutenza 4 78.12 Quite High
antagonist 6 73.96 Quite High
Deafferentation 2 72.88 Quite High
Disease Link Frequency Relevance Heat
Peptic Ulcer 2 93.28 High High
Targeted Disruption 4 82.52 Quite High
Ulcers 2 75.00 Quite High
Acid Reflux 2 56.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The underlying mechanisms of these actions of PGE2 in the stomach, duodenum, or small intestine are related to inhibition of stomach contraction (EP1), stimulation of duodenal HCO3- secretion (EP3/EP4), or suppression of bacterial invasion due to inhibition of intestinal contraction (EP4) and stimulation of mucus secretion (EP3/EP4) respectively, although the mechanisms related to the esophageal protection remain unknown.
Regulation (related) of Localization (secretion) of EP3 in duodenum
1) Confidence 0.32 Published 2010 Journal Adv Clin Chem Section Abstract Doc Link 20857620 Disease Relevance 0.39 Pain Relevance 0.36
The underlying mechanisms of these actions of PGE2 in the stomach, duodenum, or small intestine are related to inhibition of stomach contraction (EP1), stimulation of duodenal HCO3- secretion (EP3/EP4), or suppression of bacterial invasion due to inhibition of intestinal contraction (EP4) and stimulation of mucus secretion (EP3/EP4) respectively, although the mechanisms related to the esophageal protection remain unknown.
Regulation (related) of in stomach Localization (secretion) of EP3 in duodenum
2) Confidence 0.11 Published 2010 Journal Adv Clin Chem Section Abstract Doc Link 20857620 Disease Relevance 0.39 Pain Relevance 0.36

General Comments

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