INT169800

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Context Info
Confidence 0.39
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.04
Pain Relevance 1.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Adrbk1, Mapk1) signal transduction (Adrbk1, Mapk1) kinase activity (Adrbk1, Mapk1)
nucleoplasm (Mapk1) mitochondrion (Mapk1) protein complex (Mapk1)
Adrbk1 (Mus musculus)
Mapk1 (Mus musculus)
Pain Link Frequency Relevance Heat
Hyperalgesia 10 92.64 High High
nociceptor 5 76.08 Quite High
nav1.8 1 75.24 Quite High
Inflammation 6 73.28 Quite High
IPN 1 58.88 Quite High
hyperexcitability 1 53.60 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 10 92.64 High High
INFLAMMATION 4 68.20 Quite High
Inflammatory Pain 1 58.88 Quite High
Nociception 1 54.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vitro, GRK2 deficiency increased 8-pCPT-induced activation of the downstream effector of Epac, Rap1, and extracellular signal-regulated kinase (ERK).
Negative_regulation (deficiency) of GRK2 Positive_regulation (increased) of Positive_regulation (activation) of extracellular signal-regulated kinase
1) Confidence 0.39 Published 2010 Journal J. Neurosci. Section Abstract Doc Link 20861385 Disease Relevance 1.04 Pain Relevance 1.45

General Comments

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