INT169932

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Context Info
Confidence 0.13
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (H47) enzyme binding (H47) cytoplasm (H47)
H47 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 4 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acute Erythroblastic Leukemia 2 99.56 Very High Very High Very High
Hyperplasia 2 88.88 High High
Apoptosis 6 71.44 Quite High
Cancer 9 5.00 Very Low Very Low Very Low
Repression 4 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Bladder Cancer 1 5.00 Very Low Very Low Very Low
Myelodysplastic Syndromes 1 5.00 Very Low Very Low Very Low
Retinoblastoma 1 5.00 Very Low Very Low Very Low
Breast Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been reported that the second generation of HPCs (suberoylanilide hydroxamic acid [SAHA]), structurally related to but 2000-fold more potent than HMBA, was an inhibitor of histone deacetylase activity and caused accumulation of hyperacetylated histone H4 in murine erythroleukemia.


Positive_regulation (caused) of Positive_regulation (accumulation) of H4 associated with acute erythroblastic leukemia
1) Confidence 0.13 Published 2001 Journal Breast Cancer Res Section Body Doc Link PMC13923 Disease Relevance 0.26 Pain Relevance 0

General Comments

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