INT170051

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.43
First Reported 2001
Last Reported 2010
Negated 6
Speculated 4
Reported most in Body
Documents 150
Total Number 154
Disease Relevance 56.75
Pain Relevance 16.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Gopc) Golgi apparatus (Gopc) plasma membrane (Gopc)
cytoplasm (Gopc)
Anatomy Link Frequency
neurons 14
muscle 8
tear 6
vessels 4
smooth muscle cells 4
Gopc (Mus musculus)
Gopc - D849N (1)
Pain Link Frequency Relevance Heat
Inflammation 800 100.00 Very High Very High Very High
b2 receptor 116 100.00 Very High Very High Very High
amygdala 98 100.00 Very High Very High Very High
Sciatic nerve 43 100.00 Very High Very High Very High
Nicotine 386 99.98 Very High Very High Very High
antagonist 389 99.68 Very High Very High Very High
Neuritis 6 99.68 Very High Very High Very High
cocaine 7 99.52 Very High Very High Very High
long-term potentiation 92 99.26 Very High Very High Very High
Neurotransmitter 41 99.16 Very High Very High Very High
Disease Link Frequency Relevance Heat
Cancer 1004 100.00 Very High Very High Very High
INFLAMMATION 899 100.00 Very High Very High Very High
Targeted Disruption 851 100.00 Very High Very High Very High
Stress 728 100.00 Very High Very High Very High
Disease 701 100.00 Very High Very High Very High
Disorders Of The Lacrimal System 183 100.00 Very High Very High Very High
Vasculitis 92 100.00 Very High Very High Very High
Apoptosis 585 99.96 Very High Very High Very High
Injury 295 99.70 Very High Very High Very High
Obesity 205 99.70 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The radial distance values in Fig. 3B, Table 1 cover also the range above 100 ?
Positive_regulation (cover) of Gene_expression (cover) of Fig in radial
1) Confidence 0.43 Published 2010 Journal Neuroscience Section Body Doc Link PMC2954315 Disease Relevance 0 Pain Relevance 0
These cells were able to differentiate into acinar cells as also indicated by the increase in expression of the key enzyme amylase, analyzed either by immuno-histochemistry (Fig. 3A) and RT-PCR (Fig. 3B).
Positive_regulation (increase) of Spec (analyzed) Gene_expression (expression) of Fig in acinar cells
2) Confidence 0.35 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2329592 Disease Relevance 0 Pain Relevance 0
These cells were able to differentiate into acinar cells as also indicated by the increase in expression of the key enzyme amylase, analyzed either by immuno-histochemistry (Fig. 3A) and RT-PCR (Fig. 3B).
Positive_regulation (increase) of Spec (analyzed) Gene_expression (expression) of Fig in acinar cells
3) Confidence 0.35 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2329592 Disease Relevance 0 Pain Relevance 0
Indeed, as shown in Fig. 1B, Juvenile Thalamo-LA synapses typically behave as phasic synapses [31] with a small amount of PPR [1.23±0.07, n?
Positive_regulation (-) of Gene_expression (shown) of Fig in synapses associated with amygdala
4) Confidence 0.35 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2896423 Disease Relevance 0.05 Pain Relevance 0.36
An example of a two-pathway LTP experiment perfomed using an MEA is demonstrated in Fig. 5.
Positive_regulation (demonstrated) of Gene_expression (demonstrated) of Fig associated with long-term potentiation
5) Confidence 0.35 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1574331 Disease Relevance 0.11 Pain Relevance 0.11
Occasional small foci of inflammatory infiltrates were observed in AAV-transduced mKO muscles, often nearby myofibers expressing high levels of myotubularin (Fig. 3C).
Positive_regulation (levels) of Gene_expression (expressing) of Fig in muscles associated with inflammation
6) Confidence 0.32 Published 2008 Journal Human Molecular Genetics Section Body Doc Link PMC2441725 Disease Relevance 0.36 Pain Relevance 0.05
Results from DOS measurements are shown in Fig. 3
Positive_regulation (Results) of Gene_expression (shown) of Fig
7) Confidence 0.31 Published 2010 Journal Biomedical Optics Express Section Body Doc Link PMC3018079 Disease Relevance 0.26 Pain Relevance 0.04
5) could cause activation of P2X2 channels expressed in HEK293 cells in the system (Fig. 3a, b) although time to activation of P2X2-mediated currents varied because of the stopped flow and the fact that it requires 1–2 min for 4?
Positive_regulation (activation) of Gene_expression (expressed) of Fig
8) Confidence 0.28 Published 2009 Journal Pflugers Arch Section Body Doc Link PMC2745623 Disease Relevance 0 Pain Relevance 0.08
Complement, part of the innate immune system, can be activated by at least three separate pathways: the classical, alternative, and lectin pathways (Figure 1 (Fig. 1)).
Positive_regulation (activated) of Gene_expression (pathways) of Fig in immune system
9) Confidence 0.28 Published 2010 Journal GMS German Medical Science Section Body Doc Link PMC2940219 Disease Relevance 1.12 Pain Relevance 0.25
On the contrary, T0901317 (20 mg/kg) treatment prevented the carrageenan-induced Bax expression (Fig. 7Ae, see densitometry analysis 7Ae1).
Positive_regulation (induced) of Gene_expression (expression) of Fig
10) Confidence 0.28 Published 2010 Journal Respir Res Section Body Doc Link PMC2836283 Disease Relevance 0.52 Pain Relevance 0.03
In addition, MoSP2 and two other protease-sensitive synthetic prion isolates transmitted disease to Tg4053 mice overexpressing MoPrP (Fig. 4).
Positive_regulation (overexpressing) of Gene_expression (overexpressing) of Fig associated with disease
11) Confidence 0.27 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2809756 Disease Relevance 0.89 Pain Relevance 0
In contrast, a slight increase in serum ketones in both fed and fasted animals (Table 1), together with unchanged levels of HMG-CoA synthase mRNA (Fig. 6B) and a significant increase in propionyl-CoA, an odd chain ?
Positive_regulation (increase) of Gene_expression (synthase mRNA) of Fig
12) Confidence 0.27 Published 2008 Journal Diabetes Section Body Doc Link PMC2494684 Disease Relevance 0.28 Pain Relevance 0
In contrast, a slight increase in serum ketones in both fed and fasted animals (Table 1), together with unchanged levels of HMG-CoA synthase mRNA (Fig. 6B) and a significant increase in propionyl-CoA, an odd chain ?
Positive_regulation (increase) of Gene_expression (synthase mRNA) of Fig
13) Confidence 0.27 Published 2008 Journal Diabetes Section Body Doc Link PMC2494684 Disease Relevance 0.27 Pain Relevance 0
Experimental design to determine c-Fos expression pattern: protocol 2 (Fig. 1A).
Spec (determine) Positive_regulation (determine) of Spec (determine) Gene_expression (expression) of Fig
14) Confidence 0.26 Published 2008 Journal Diabetes Section Body Doc Link PMC2551668 Disease Relevance 0.16 Pain Relevance 0.06
The Akt phosphorylation induced by insulin was enhanced upon Hsp72 overexpression (Fig. 9A,B).
Positive_regulation (overexpression) of Gene_expression (overexpression) of Fig
15) Confidence 0.26 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2603588 Disease Relevance 0.56 Pain Relevance 0
Consequently, this treatment enhanced the insulin-stimulated Akt phosphorylation in HepG2 cells exposed to high glucose similar to Hsp72 overexpression (Fig. 9D,E).
Positive_regulation (overexpression) of Gene_expression (overexpression) of Fig
16) Confidence 0.26 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2603588 Disease Relevance 0.85 Pain Relevance 0
The Akt phosphorylation induced by insulin was enhanced upon Hsp72 overexpression (Fig. 9A,B).
Positive_regulation (enhanced) of Gene_expression (overexpression) of Fig
17) Confidence 0.26 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2603588 Disease Relevance 0.56 Pain Relevance 0
We observed increased expression of IL-10 on the sciatic nerve of Tg+ healthy and sick mice (Fig.
Positive_regulation (increased) of Gene_expression (expression) of Fig in sciatic nerve associated with sciatic nerve
18) Confidence 0.26 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2743195 Disease Relevance 0.65 Pain Relevance 0.24
Therefore, it is reasonable to propose that NGF secreted by melanoma tumor was transferred through blood and bound to its cognate receptors in the salivary gland, ultimately resulting in the stimulation of multiple TFs expression including Egr-1 (Fig. 6).
Positive_regulation (multiple) of Gene_expression (expression) of Fig in blood associated with nerve growth factor, cancer and melanoma
19) Confidence 0.25 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2691577 Disease Relevance 1.48 Pain Relevance 0.39
external probe (Fig. 1A) generated using: 5?
Positive_regulation (generated) of Gene_expression (probe) of Fig in external
20) Confidence 0.25 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2565062 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox