INT170054

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Context Info
Confidence 0.38
First Reported 2001
Last Reported 2011
Negated 5
Speculated 2
Reported most in Body
Documents 280
Total Number 282
Disease Relevance 117.89
Pain Relevance 42.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Gopc) Golgi apparatus (Gopc) plasma membrane (Gopc)
cytoplasm (Gopc)
Anatomy Link Frequency
plasma 5
neurons 5
neuronal 4
retinas 3
lung 3
Gopc (Mus musculus)
Gopc - Y1012A (1) Gopc - F1012A (1)
Pain Link Frequency Relevance Heat
Inflammation 1427 100.00 Very High Very High Very High
cytokine 645 100.00 Very High Very High Very High
Spinal cord 370 100.00 Very High Very High Very High
Glutamate 332 100.00 Very High Very High Very High
Hippocampus 243 100.00 Very High Very High Very High
diclofenac 190 100.00 Very High Very High Very High
Eae 168 100.00 Very High Very High Very High
tetrodotoxin 90 100.00 Very High Very High Very High
medulla 52 100.00 Very High Very High Very High
Serotonin 33 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Cancer 2947 100.00 Very High Very High Very High
INFLAMMATION 1623 100.00 Very High Very High Very High
Targeted Disruption 1412 100.00 Very High Very High Very High
Apoptosis 1118 100.00 Very High Very High Very High
Diabetes Mellitus 981 100.00 Very High Very High Very High
Infection 889 100.00 Very High Very High Very High
Sprains And Strains 645 100.00 Very High Very High Very High
Death 558 100.00 Very High Very High Very High
Injury 539 100.00 Very High Very High Very High
Adhesions 123 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This reduction was associated with a loss of CD4+CD8+ DP cells (Fig. 7D).
Negative_regulation (loss) of Fig in DP cells
1) Confidence 0.38 Published 2007 Journal Virol J Section Body Doc Link PMC1810241 Disease Relevance 1.71 Pain Relevance 0
Administration of diazepam at a dose of 3 mg/kg significantly (p < 0.01) suppressed the locomotor activity (Fig. 3).


Negative_regulation (suppressed) of Fig associated with eae
2) Confidence 0.37 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2972602 Disease Relevance 0 Pain Relevance 0.31
In the experiments represented in Fig. 3A, significant mechanical allodynia was observed in the tumour group at day 7 after tumour implantation, which increased further in magnitude at day 12.
Negative_regulation (represented) of Fig associated with allodynia and cancer
3) Confidence 0.36 Published 2010 Journal Mol Pain Section Body Doc Link PMC2855524 Disease Relevance 1.60 Pain Relevance 0.58
A simulation of the effect of a proteasome inhibitor is given in Fig. 9 and Fig. 10, and corresponds to the untreated tumor simulations illustrated in Fig. 4 and Fig. 5.
Negative_regulation (given) of Fig associated with cancer
4) Confidence 0.36 Published 2010 Journal Biol Direct Section Body Doc Link PMC2867965 Disease Relevance 0.92 Pain Relevance 0
= [0, 1], the regular spatial and temporal cycles of the osteoclast and osteoblast populations are disrupted with these solutions ultimately approaching the zero-dimensional tumor model nontrivial steady state = 5.0, = 316.0, as in Fig. 4 (Fig. 14), the bone mass is depleted throughout ?
Negative_regulation (depleted) of Fig in osteoclast associated with cancer and osteoporosis
5) Confidence 0.36 Published 2010 Journal Biol Direct Section Body Doc Link PMC2867965 Disease Relevance 0.95 Pain Relevance 0
= [0, 1], the regular spatial and temporal cycles of the osteoclast and osteoblast populations are disrupted with these solutions ultimately approaching the zero-dimensional tumor model nontrivial steady state = 5.0, = 316.0, as in Fig. 4 (Fig. 14), the bone mass is depleted throughout ?
Negative_regulation (depleted) of Fig in osteoclast associated with cancer and osteoporosis
6) Confidence 0.36 Published 2010 Journal Biol Direct Section Body Doc Link PMC2867965 Disease Relevance 0.96 Pain Relevance 0
A simulation of the effect of a proteasome inhibitor is given in Fig. 9 and Fig. 10, and corresponds to the untreated tumor simulations illustrated in Fig. 4 and Fig. 5.
Negative_regulation (given) of Fig associated with cancer
7) Confidence 0.36 Published 2010 Journal Biol Direct Section Body Doc Link PMC2867965 Disease Relevance 0.92 Pain Relevance 0
urea cycle-related amino acids versus urea in plasma are depicted in Fig. 4A, and ?
Negative_regulation (depicted) of Fig in plasma
8) Confidence 0.36 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2970564 Disease Relevance 0.07 Pain Relevance 0.11
The OI intensities in the tumor and the normal tissue as a function of time for [18F]FDG was depicted in Fig. 3F, while accumulation of radioactivity in tumor and muscle over time was shown in Fig. 3G.
Negative_regulation (depicted) of Fig in muscle associated with cancer and imagery
9) Confidence 0.35 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2830426 Disease Relevance 0.83 Pain Relevance 0.52
As exemplified in Fig. 5A and shown quantitatively in Fig. 5B, the c-Fos-positive cell density of the test group was the greatest of the three groups and was located in supragranular layers II and III in particular.
Negative_regulation (shown) of Fig
10) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2864740 Disease Relevance 0 Pain Relevance 0.07
In the PCDM analysis (Fig. 3), both the unilateral and bilateral stimulation groups yielded c-Fos expression in the barrel fields of the primary somatosensory cortex.
Negative_regulation (yielded) of Fig in primary somatosensory cortex associated with primary somatosensory cortex
11) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2864740 Disease Relevance 0 Pain Relevance 0.09
Fig. 5 shows strain-dependent total von Frey allodynia of the ipsilateral hind paw (Fig. 5A), CatWalk total mean intensity decreases in the ipsilateral hind paw (Fig. 5B), and their correlation (Fig. 5C).
Negative_regulation (decreases) of Fig in paw associated with allodynia and sprains and strains
12) Confidence 0.34 Published 2010 Journal Mol Pain Section Body Doc Link PMC2893131 Disease Relevance 0.76 Pain Relevance 0.18
To confirm the presence of donor cells in the tissues detected by ex vivo fluorescent imaging, sections of the tissues were examined for presence of EGFP+ cells 24 h after transplantation (Fig. 3D).
Spec (examined) Negative_regulation (presence) of Fig associated with imagery
13) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2885427 Disease Relevance 0 Pain Relevance 0.33
S3 A, B) and they were still reduced by 2MeSADP treatment (Fig.
Negative_regulation (reduced) of Fig
14) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3008710 Disease Relevance 0.25 Pain Relevance 0
We demonstrated that a threefold speedup still provides high-quality T1 parameter maps (Fig. 7c) and reproducible T1 values (Table 2), reducing the scan time from ?
Negative_regulation (provides) of Fig
15) Confidence 0.32 Published 2011 Journal Magnetic Resonance in Medicine Section Body Doc Link PMC3021721 Disease Relevance 0 Pain Relevance 0.15
30% reduction in amperometric spike charge in sdy cells (Fig. 1, D and E).
Negative_regulation (reduction) of Fig in spike
16) Confidence 0.31 Published 2008 Journal The Journal of Cell Biology Section Body Doc Link PMC2396815 Disease Relevance 0.05 Pain Relevance 0.12
l per side) into the ACC of male mice significantly reduced sexual attraction in the first 10 min (Fig. 3A and 3B).
Negative_regulation (reduced) of Fig associated with anterior cingulate cortex
17) Confidence 0.30 Published 2009 Journal Mol Brain Section Body Doc Link PMC2685783 Disease Relevance 0 Pain Relevance 0.58
Mean spine head diameters were significantly reduced following a 5 h midazolam anesthesia at PND 20, and less at PND 30 (mean decrease at PND 15: 35±1.2%; at PND 20: 37±4%; at PND 30: 10±2%; P<0.01, Fig. 1c).
Negative_regulation (decrease) of Fig in head associated with anesthesia and versed
18) Confidence 0.30 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2738943 Disease Relevance 0 Pain Relevance 1.02
Similarly to midazolam, these two drugs also induced an age-dependent significant increase in dendritic spine density (Fig. 2a, b, P<0.05) as well as a simultaneous decrease in average dendritic spine head diameter (Fig. 2c: PND 15, P<0.05).
Negative_regulation (decrease) of Fig in spine associated with versed
19) Confidence 0.30 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2738943 Disease Relevance 0 Pain Relevance 0.75
It is also used to control tumescent anesthesia infiltration, cannula position prior to laser emission, and postoperative fat liquefaction.Fig. 2Ultrasound imaging probe used to determine the volume to be treated and the thickness of the fat layer

Technique

Negative_regulation (postoperative) of Fig in fat associated with anesthesia and imagery
20) Confidence 0.30 Published 2008 Journal Aesthetic Plast Surg Section Body Doc Link PMC2696609 Disease Relevance 0.08 Pain Relevance 0.32

General Comments

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