INT17009

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Context Info
Confidence 0.08
First Reported 1991
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.97
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (CADPS) cytosol (CADPS)
Anatomy Link Frequency
platelet 1
CADPS (Homo sapiens)
Pain Link Frequency Relevance Heat
local anesthetic 1 96.88 Very High Very High Very High
Demyelination 3 94.80 High High
Inflammation 6 65.32 Quite High
Central nervous system 6 52.48 Quite High
headache 10 30.80 Quite Low
cva 30 5.00 Very Low Very Low Very Low
Multiple sclerosis 19 5.00 Very Low Very Low Very Low
imagery 13 5.00 Very Low Very Low Very Low
Migraine 7 5.00 Very Low Very Low Very Low
aspirin 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anti-phospholipid Antibody Syndrome 119 98.70 Very High Very High Very High
Demyelinating Disease 24 94.80 High High
Syndrome 44 86.68 High High
Recurrence 3 86.48 High High
Hemorrhage 2 80.88 Quite High
Thrombosis Related Under Development 41 78.16 Quite High
Systemic Lupus Erythematosus 58 73.40 Quite High
Neuropathic Pain 1 72.52 Quite High
INFLAMMATION 5 65.32 Quite High
Neurological Disease 3 64.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Discussion of therapeutic approaches in APS is beyond the scope of this overview, but most recent advances, especially in CAPS which is the most life-threatening variant of APS, are listed briefly as follows:
Regulation (especially) of CAPS associated with anti-phospholipid antibody syndrome
1) Confidence 0.08 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628175 Disease Relevance 1.97 Pain Relevance 0.14
Effects of the organic solvent toluene on the platelet membrane receptor glycoprotein Ib (GP Ib) and the cytoskeletal protein, actin-binding protein (ABP), were studied and related to the effects of the local anesthetic dibucaine.
Regulation (Effects) of cytoskeletal protein in platelet associated with local anesthetic
2) Confidence 0.00 Published 1991 Journal Biochem. Pharmacol. Section Abstract Doc Link 1867638 Disease Relevance 0 Pain Relevance 0.10

General Comments

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