INT170128

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Context Info
Confidence 0.04
First Reported 1999
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.60
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (ITGAL, ITGB2) plasma membrane (ITGAL, ITGB2) signal transduction (ITGAL)
cell-cell signaling (ITGB2)
ITGAL (Homo sapiens)
ITGB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
psoriasis 68 84.84 Quite High
cytokine 45 79.60 Quite High
Inflammation 13 79.04 Quite High
Infliximab 15 5.00 Very Low Very Low Very Low
Etanercept 13 5.00 Very Low Very Low Very Low
Adalimumab 8 5.00 Very Low Very Low Very Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
Multiple sclerosis 3 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 27 100.00 Very High Very High Very High
Disease 18 94.72 High High
Psoriasis 76 84.84 Quite High
INFLAMMATION 14 79.04 Quite High
Respiratory Distress 1 72.72 Quite High
Multiple Organ Failure 6 70.00 Quite High
Critical Illness 5 50.00 Quite Low
Leukocytosis 1 20.96 Low Low
Mycobacterial Infection 8 5.00 Very Low Very Low Very Low
Demyelinating Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The

CD11a-c/CD18 adhesion molecules are the most important integrins, whereas CD62L is the most important member of the selectin family.

CD11a Binding (integrins) of CD18 associated with adhesions
1) Confidence 0.04 Published 1999 Journal Crit Care Section Body Doc Link PMC29032 Disease Relevance 1.09 Pain Relevance 0.15
Anti-CD11a antibody: Efalizumab: LFA-1, a heterodimer of CD11a and CD18, is a member of the ?
LFA-1 Binding (heterodimer) of CD18
2) Confidence 0.01 Published 2008 Journal Indian Journal of Pharmacology Section Body Doc Link PMC2792605 Disease Relevance 0.51 Pain Relevance 0.13

General Comments

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