INT17019

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Context Info
Confidence 0.70
First Reported 1987
Last Reported 1991
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.85
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (AHSP) protein folding (AHSP) cytoplasm (AHSP)
Anatomy Link Frequency
vessels 1
platelet 1
AHSP (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 1 89.00 High High
Angina 3 85.32 High High
Serotonin 3 82.24 Quite High
5HT 1 81.36 Quite High
antagonist 1 81.08 Quite High
aspirin 1 70.00 Quite High
Disease Link Frequency Relevance Heat
Injury 1 98.08 Very High Very High Very High
Increased Venous Pressure Under Development 9 96.04 Very High Very High Very High
Stress 1 87.24 High High
Hypertension 4 85.88 High High
Cv General 3 Under Development 3 85.32 High High
Myocardial Infarction 1 85.00 Quite High
Coronary Vasospasm 3 82.12 Quite High
Syndrome 1 79.84 Quite High
Hypoxia 4 69.32 Quite High
Adhesions 1 58.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In porcine coronary vessels the amount of EDRF released can be increased by a diet of codliver oil and decreased by a high cholesterol diet.
Positive_regulation (increased) of EDRF in vessels
1) Confidence 0.70 Published 1991 Journal J. Mol. Cell. Cardiol. Section Abstract Doc Link 2038073 Disease Relevance 0.54 Pain Relevance 0.25
As both prostaglandin I2 and acetylcholine-induced EDRF also inhibit platelet aggregation, endothelial injury and loss of these factors may predispose to vasospasm precipitated by release of platelet-derived mediators such as thromboxane A2 (TXA2) and 5-hydroxytryptamine.
Positive_regulation (induced) of EDRF in platelet associated with injury and increased venous pressure under development
2) Confidence 0.67 Published 1987 Journal Fed. Proc. Section Abstract Doc Link 3100342 Disease Relevance 0.36 Pain Relevance 0.12
The importance of EDRF to the anesthesiologist may go beyond an understanding of its role in cardiovascular physiological and pathophysiological states.
Positive_regulation (importance) of EDRF
3) Confidence 0.50 Published 1991 Journal J. Cardiothorac. Vasc. Anesth. Section Abstract Doc Link 1868189 Disease Relevance 0.95 Pain Relevance 0.13

General Comments

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