INT170298

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Context Info
Confidence 0.01
First Reported 2001
Last Reported 2001
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.48
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear chromosome (Hmga2) enzyme binding (Hmga2) DNA binding (Hmga2)
mitosis (Hmga2) signal transduction (Hmga2) nucleus (Hmga2)
Hmga2 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 33 78.24 Quite High
Serotonin 6 31.52 Quite Low
Inflammation 12 5.00 Very Low Very Low Very Low
cytokine 9 5.00 Very Low Very Low Very Low
cINOD 6 5.00 Very Low Very Low Very Low
Inflammatory mediators 6 5.00 Very Low Very Low Very Low
tolerance 6 5.00 Very Low Very Low Very Low
COX-2 inhibitor 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 84 86.28 High High
Apoptosis 3 64.12 Quite High
INFLAMMATION 21 5.00 Very Low Very Low Very Low
Cancer 18 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 9 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 9 5.00 Very Low Very Low Very Low
Chlamydia Infection 6 5.00 Very Low Very Low Very Low
Fibrosarcoma 6 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Wound Healing 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, similar effects on cell morphology were produced by opposite effects on COX-2 expression and PG E2 production in these two cell lines.
Regulation (effects) of Gene_expression (production) of PG E2
1) Confidence 0.01 Published 2001 Journal BMC Biochem Section Body Doc Link PMC31925 Disease Relevance 0.34 Pain Relevance 0.04
However, PG E2 production was affected relatively little compared to the other PGs.
Neg (little) Regulation (affected) of Gene_expression (production) of PG E2
2) Confidence 0.01 Published 2001 Journal BMC Biochem Section Body Doc Link PMC31925 Disease Relevance 0.14 Pain Relevance 0.04
If increased PG E2 production relative to other PGs was responsible for the appearance of macroscopic foci, then adding back increasing amounts of other PGs such as D2 and F2?
Regulation (responsible) of Gene_expression (production) of PG E2
3) Confidence 0.01 Published 2001 Journal BMC Biochem Section Body Doc Link PMC31925 Disease Relevance 0 Pain Relevance 0

General Comments

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