INT1703

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Context Info
Confidence 0.52
First Reported 1978
Last Reported 2010
Negated 5
Speculated 3
Reported most in Abstract
Documents 52
Total Number 55
Disease Relevance 23.65
Pain Relevance 20.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
respiratory 2
liver 1
anterior 1
PCA 1
thoracic 1
PCa (Homo sapiens)
Pain Link Frequency Relevance Heat
Patient controlled alalgesia 96 100.00 Very High Very High Very High
sodium channel 82 100.00 Very High Very High Very High
Morphine 62 100.00 Very High Very High Very High
Pain 59 100.00 Very High Very High Very High
analgesia 45 100.00 Very High Very High Very High
Opioid 17 100.00 Very High Very High Very High
Patient controlled epidural analgesia 4 100.00 Very High Very High Very High
monoamine 2 100.00 Very High Very High Very High
medulla 3 99.88 Very High Very High Very High
cytokine 24 99.76 Very High Very High Very High
Disease Link Frequency Relevance Heat
Prostate Cancer 458 100.00 Very High Very High Very High
Reprotox - General 1 211 100.00 Very High Very High Very High
Pancreatic Cancer 188 100.00 Very High Very High Very High
Pain 75 100.00 Very High Very High Very High
Burns 6 99.84 Very High Very High Very High
Post-operative Nausea 3 99.64 Very High Very High Very High
Post Operative Pain 28 99.60 Very High Very High Very High
Mucositis 5 99.46 Very High Very High Very High
Respiratory Failure 13 99.12 Very High Very High Very High
Disease 108 98.88 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSION: Combination of low-dose nalbuphine and morphine in PCA decreases the incidence of opioid-related nausea, without affecting the analgesia and PCA requirement.
Neg (without) Regulation (affecting) of PCA
1) Confidence 0.52 Published 2009 Journal J. Formos. Med. Assoc. Section Body Doc Link 19586828 Disease Relevance 0.05 Pain Relevance 0
In adults, patient-controlled analgesia (PCA) is widely administered, while in children, its use with opioid drugs is still under evaluation for safety and efficacy.
Regulation (controlled) of PCA associated with opioid
2) Confidence 0.38 Published 2008 Journal Childs Nerv Syst Section Abstract Doc Link 17639417 Disease Relevance 0.17 Pain Relevance 0.57
STUDY OBJECTIVE: To compare ondansetron with ondansetron plus prochlorperazine, added to a patient-controlled analgesia (PCA) solution for control of postoperative nausea and vomiting (PONV).
Regulation (controlled) of PCA associated with post-operative nausea, vomiting and patient controlled alalgesia
3) Confidence 0.38 Published 2008 Journal J Clin Anesth Section Abstract Doc Link 19100932 Disease Relevance 0.52 Pain Relevance 0.25
PURPOSE: The implementation of standard order sets for patient-controlled analgesia (PCA) is described.
Regulation (controlled) of PCA associated with patient controlled alalgesia
4) Confidence 0.38 Published 2008 Journal Am J Health Syst Pharm Section Abstract Doc Link 18541691 Disease Relevance 0 Pain Relevance 0.17
An ideal patient-controlled analgesia (PCA) opioid would have both a rapid onset and a long duration of action, attributes, which are not available in currently existing opioids including morphine, the most widely used agent.
Regulation (controlled) of PCA associated with patient controlled alalgesia, opioid and morphine
5) Confidence 0.38 Published 2008 Journal Pain Pract Section Abstract Doc Link 18503621 Disease Relevance 0 Pain Relevance 1.21
INTRODUCTION: Patient-controlled analgesia (PCA) has an established role in managing postoperative pain and has been successfully used in-patients with cancer pain.
Regulation (controlled) of PCA associated with cancer pain, patient controlled alalgesia and perioperative pain
6) Confidence 0.38 Published 2010 Journal Eur J Pain Section Abstract Doc Link 19664944 Disease Relevance 0.27 Pain Relevance 0.62
Patients' assessment of the convenience of fentanyl HCl iontophoretic transdermal system (ITS) versus morphine intravenous patient-controlled analgesia (IV PCA) in the management of postoperative pain after major surgery.
Regulation (controlled) of PCA associated with transdermal, patient controlled alalgesia, perioperative pain and morphine
7) Confidence 0.38 Published 2009 Journal Pain Manag Nurs Section Title Doc Link 19706349 Disease Relevance 0.24 Pain Relevance 0.90
Although patient-controlled analgesia (PCA) is considered the standard in postoperative pain control, research examining PCA use among cognitively impaired older adults is lacking.
Regulation (controlled) of PCA associated with patient controlled alalgesia and perioperative pain
8) Confidence 0.38 Published 2009 Journal J Opioid Manag Section Abstract Doc Link 19947072 Disease Relevance 0.37 Pain Relevance 0.73
A patient-controlled analgesia (PCA) device for intravenous morphine provided free access to additional analgesics for 24 hr.
Regulation (controlled) of PCA
9) Confidence 0.38 Published 2009 Journal Masui Section Body Doc Link 19364000 Disease Relevance 0 Pain Relevance 0
The objective of the present analysis was to evaluate patients' assessment of fentanyl ITS and morphine intravenous patient-controlled analgesia (IV PCA) convenience on 7 different subscales, using a validated patient ease of care (EOC) questionnaire in 2 prospective, open-label, randomized, phase IIIb clinical trials.
Regulation (controlled) of PCA associated with patient controlled alalgesia and morphine
10) Confidence 0.38 Published 2009 Journal Pain Manag Nurs Section Abstract Doc Link 19706349 Disease Relevance 0.17 Pain Relevance 0.74
Patient controlled analgesia (PCA) can be used to manage postoperative pain.
Regulation (controlled) of PCA associated with perioperative pain and analgesia
11) Confidence 0.38 Published 2010 Journal Rev Bras Cir Cardiovasc Section Abstract Doc Link 20563466 Disease Relevance 0.20 Pain Relevance 0.37
Various analgesic modalities have been suggested including thoracic epidural analgesia and intravenous patient-controlled analgesia (IV PCA).
Regulation (controlled) of PCA in thoracic associated with analgesic, patient controlled alalgesia, epidural and analgesia
12) Confidence 0.38 Published 2009 Journal Am J Ther Section Abstract Doc Link 19262363 Disease Relevance 0.46 Pain Relevance 1.08
This report reviews the application of postoperative patient-controlled analgesia (PCA) using intravenous morphine in a single institution between 2002 and 2005.
Regulation (controlled) of PCA associated with patient controlled alalgesia and morphine
13) Confidence 0.32 Published 2009 Journal Eur J Pain Section Abstract Doc Link 18602851 Disease Relevance 0.36 Pain Relevance 0.89
BACKGROUND: Although the addition of a background infusion for intravenous patient-controlled analgesia (IV-PCA) has been identified as a risk factor for the development of respiratory depression, this has not clearly been examined in a systematic fashion.
Regulation (controlled) of IV-PCA in respiratory associated with depression, respiratory failure and patient controlled alalgesia
14) Confidence 0.32 Published 2010 Journal J Opioid Manag Section Abstract Doc Link 20297614 Disease Relevance 0.17 Pain Relevance 0.37
OBJECTIVE: This survey estimated differences in staff time requirements between fentanyl HCl iontophoretic transdermal system (fentanyl ITS) and intravenous patient-controlled analgesia (IV-PCA) in post-operative pain management.
Regulation (controlled) of IV-PCA associated with transdermal, pain management and patient controlled alalgesia
15) Confidence 0.32 Published 2009 Journal Curr Med Res Opin Section Abstract Doc Link 19192974 Disease Relevance 0.17 Pain Relevance 0.44
METHODS: Sequential patients undergoing anterolateral thoracotomy for MIDCAB, lung tumor resection, or median sternotomy for OPCAB were randomized to one of the two intravenous patient-controlled analgesia (IV-PCA) protocols.
Regulation (controlled) of IV-PCA in lung
16) Confidence 0.32 Published 2008 Journal Pharmacol. Res. Section Body Doc Link 18602474 Disease Relevance 0.18 Pain Relevance 0
In addition, intravenous patient-controlled analgesia (IV-PCA) was also used for postoperative analgesia instead of epidural analgesia.
Regulation (controlled) of IV-PCA associated with epidural, patient controlled alalgesia and analgesia
17) Confidence 0.32 Published 2008 Journal Masui Section Abstract Doc Link 18341007 Disease Relevance 1.30 Pain Relevance 0.34
Indomethacin alone induced a time-dependent PCA response; when coincubated with LPS the PCA response was greater than that produced by either indomethacin or LPS alone.
Regulation (response) of PCA
18) Confidence 0.24 Published 1995 Journal Scand. J. Gastroenterol. Section Body Doc Link 7701246 Disease Relevance 0 Pain Relevance 0
In THP-1 cells, ethanol had no significant effect on PCA in either non-challenged or LPS-induced status.
Neg (no) Regulation (effect) of PCA in THP-1
19) Confidence 0.23 Published 1991 Journal Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. Section Abstract Doc Link 1685419 Disease Relevance 0.17 Pain Relevance 0.08
Exposure of whole blood to ethanol showed no effect on PCA in human monocytes.
Neg (no) Regulation (effect) of PCA in monocytes
20) Confidence 0.23 Published 1991 Journal Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. Section Abstract Doc Link 1685419 Disease Relevance 0.16 Pain Relevance 0.09

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