INT170307

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Context Info
Confidence 0.16
First Reported 2001
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.45
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Col4a1) proteinaceous extracellular matrix (Col4a1)
Col4a1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 2 91.60 High High
cINOD 2 54.64 Quite High
cytokine 3 38.24 Quite Low
metalloproteinase 11 32.16 Quite Low
tolerance 2 11.92 Low Low
Inflammation 4 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Serotonin 2 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 59 99.08 Very High Very High Very High
Disease 3 97.36 Very High Very High Very High
Open-angle Glaucoma 17 92.08 High High
INFLAMMATION 7 91.60 High High
Glaucoma 28 86.24 High High
Eye Malformation 1 84.68 Quite High
Targeted Disruption 5 80.60 Quite High
Congenital Anomalies 8 77.76 Quite High
Adhesions 28 50.00 Quite Low
Cataract 10 37.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The alterations in COX-2 expression observed in IDO-expressing RAW and MC57 cells are a particularly interesting feature of our results.
Regulation (alterations) of Gene_expression (expression) of RAW
1) Confidence 0.16 Published 2001 Journal BMC Biochem Section Body Doc Link PMC31925 Disease Relevance 0.15 Pain Relevance 0.10
Recent immunohistological studies in NPS patients with severe glomerular disease suggest a possible regulation of type III collagen by LMX1B, while the homozygous mutations of LMX1B do not appear to dramatically affect the expression of type IV collagen chains and podocin in NPS patients.
Regulation (affect) of Gene_expression (expression) of type IV collagen associated with syndrome and disease
2) Confidence 0.05 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2669506 Disease Relevance 1.31 Pain Relevance 0

General Comments

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