INT170377

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Context Info
Confidence 0.42
First Reported 2001
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 0.37
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Eomes) nucleus (Eomes) intracellular (Eomes)
DNA binding (Eomes)
Anatomy Link Frequency
radial 1
stem cells 1
Eomes (Mus musculus)
Pain Link Frequency Relevance Heat
Anterior cingulate cortex 4 62.92 Quite High
Inflammation 20 39.20 Quite Low
cytokine 32 38.16 Quite Low
chemokine 4 37.12 Quite Low
cINOD 40 5.00 Very Low Very Low Very Low
Eae 24 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
cerebral cortex 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 10 92.20 High High
Congenital Anomalies 24 65.76 Quite High
Neurodegenerative Disease 44 57.44 Quite High
Infection 68 54.36 Quite High
Schizophrenia 32 51.32 Quite High
INFLAMMATION 44 39.20 Quite Low
Viral Infection 12 24.96 Low Low
Death 4 17.96 Low Low
Autism 24 5.00 Very Low Very Low Very Low
Influenza Virus Infection 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
C) on neural stem/progenitor cells (NPC) proliferation, we quantitated the intracellular expression of PAX6 and TBR2 in subtypes of NPC, radial glia (RG) cells and intermediate progenitor cells (IPC).
Gene_expression (expression) of TBR2 in radial
1) Confidence 0.42 Published 2010 Journal mBio Section Body Doc Link PMC2953007 Disease Relevance 0 Pain Relevance 0
The transition from RG to IPC occurs with a sequential increase in the expression of TBR2, followed by a reduction in PAX6 expression.
Gene_expression (expression) of TBR2
2) Confidence 0.42 Published 2010 Journal mBio Section Body Doc Link PMC2953007 Disease Relevance 0.17 Pain Relevance 0.03
C) and BrdU and analyzed by flow cytometry for expression of TBR2 and PAX6.
Spec (analyzed) Gene_expression (expression) of TBR2
3) Confidence 0.42 Published 2010 Journal mBio Section Body Doc Link PMC2953007 Disease Relevance 0 Pain Relevance 0
This is most definitively demonstrated by an increase in the expansion of PAX6+ RG stem cells and a concurrent decrease in the TBR2-expressing IPC (see Fig. 
Gene_expression (expressing) of TBR2 in stem cells
4) Confidence 0.33 Published 2010 Journal mBio Section Body Doc Link PMC2953007 Disease Relevance 0.11 Pain Relevance 0
In Northern analysis using single stranded probes generated from the mNoc 3' UTR or from exon II, we found that in contrast to our prior work in Xenopus, mNoc is expressed as a single mRNA of about 3 kb (Fig. 2).
Gene_expression (expressed) of Xenopus
5) Confidence 0.01 Published 2001 Journal BMC Dev Biol Section Body Doc Link PMC32249 Disease Relevance 0.09 Pain Relevance 0

General Comments

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