INT1705

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Context Info
Confidence 0.65
First Reported 1978
Last Reported 2011
Negated 2
Speculated 3
Reported most in Body
Documents 126
Total Number 131
Disease Relevance 88.65
Pain Relevance 34.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
monocyte 4
neural 3
muscles 3
margins 2
PCA 2
PCa (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 194 100.00 Very High Very High Very High
Patient controlled alalgesia 178 100.00 Very High Very High Very High
analgesia 115 100.00 Very High Very High Very High
depression 80 100.00 Very High Very High Very High
antagonist 39 100.00 Very High Very High Very High
Ultiva 3 100.00 Very High Very High Very High
Desipramine 3 100.00 Very High Very High Very High
fluoxetine 2 100.00 Very High Very High Very High
sodium channel 410 99.98 Very High Very High Very High
Morphine 124 99.98 Very High Very High Very High
Disease Link Frequency Relevance Heat
Prostate Cancer 2024 100.00 Very High Very High Very High
Cancer 1708 100.00 Very High Very High Very High
Reprotox - General 1 1002 100.00 Very High Very High Very High
Pancreatic Cancer 438 100.00 Very High Very High Very High
Pancreatitis 219 100.00 Very High Very High Very High
Cystadenoma 126 100.00 Very High Very High Very High
Depression 56 100.00 Very High Very High Very High
Metastasis 472 99.96 Very High Very High Very High
Hypoalagesia 2 99.96 Very High Very High Very High
Respiratory Failure 28 99.88 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Four agents, (hydrocortisone, indomethacin, ibuprofen and acetylsalicylic acid (ASA)) used to both block production of prostaglandins and ameliorate the deleterious effects of LPS in vivo were tested on the production of rabbit M phi PCA in vitro in homogeneous cultures.
Gene_expression (production) of PCA associated with aspirin
1) Confidence 0.65 Published 1986 Journal J. Surg. Res. Section Abstract Doc Link 3081762 Disease Relevance 0.45 Pain Relevance 0.26
This review evaluates the effects of drugs such as MDMA, pCA, fenfluramine, and fluoxetine on serotonergic transmission in the brain, examines the relationships of these drug effects with the neuroendocrine mechanisms modulating reproductive events such as gonadotropin secretion, ovulation, spermatogenesis, and sexual behavior in animal models, and discusses possible reproductive implications of these drugs in humans.
Gene_expression (fluoxetine) of pCA in brain associated with fluoxetine
2) Confidence 0.65 Published 2009 Journal Cent Nerv Syst Agents Med Chem Section Abstract Doc Link 20021359 Disease Relevance 0.48 Pain Relevance 0.41
Seventy seven per cent responded that PCA is effective in the pain relief during position change, pulmonary physiotherapy and induced early ambulation.
Gene_expression (effective) of PCA associated with pain and patient controlled alalgesia
3) Confidence 0.59 Published 2001 Journal Masui Section Abstract Doc Link 11712354 Disease Relevance 0.43 Pain Relevance 2.03
Overwhelmingly, human factors were the main cause of PCA errors.
Gene_expression (cause) of PCA
4) Confidence 0.59 Published 2008 Journal Am J Health Syst Pharm Section Body Doc Link 18281735 Disease Relevance 0 Pain Relevance 0
CONCLUSION: Ramosetron was superior to ondansetron in terms of preventing vomiting and reducing the severity of nausea related to fentanyl-based IV PCA, with less adverse events, in patients with high susceptibility, undergoing lumbar spine surgery.


Gene_expression (based) of PCA in superior
5) Confidence 0.57 Published 2008 Journal Spine Section Body Doc Link 18670328 Disease Relevance 0 Pain Relevance 0
Numerical rating score, PCA requirement, nausea, vomiting, use of antiemetics, pruritus, use of antipruritics, and opioid-related adverse events were investigated at 1, 2, 4, and 24 hours postoperatively.
Gene_expression (requirement) of PCA
6) Confidence 0.57 Published 2009 Journal J. Formos. Med. Assoc. Section Body Doc Link 19586828 Disease Relevance 0.08 Pain Relevance 0
The adjusted odds of vomiting doubled for every 12 hours for Group C patients when receiving PCA.
Gene_expression (receiving) of PCA
7) Confidence 0.57 Published 2008 Journal J Clin Anesth Section Body Doc Link 19100932 Disease Relevance 0 Pain Relevance 0
In the PCA of the barriers instrument, the first iteration of the PCA found that two of the barriers to walking, hot weather and cold weather, did not significantly load onto any of the factors.
Gene_expression (iteration) of PCA
8) Confidence 0.57 Published 2006 Journal Prev Chronic Dis Section Body Doc Link PMC1779280 Disease Relevance 0.18 Pain Relevance 0.09
By comparison, only 1 incident of hypoglycemia was detected with the PCA during the same period.
Gene_expression (detected) of PCA
9) Confidence 0.57 Published 2010 Journal Am. J. Vet. Res. Section Body Doc Link 20043775 Disease Relevance 0 Pain Relevance 0
In conclusion, spontaneous isolated dissection of PCA is one of the causes of ischemic stroke in young adults.
Gene_expression (dissection) of PCA in PCA associated with stroke
10) Confidence 0.57 Published 2009 Journal Zh Nevrol Psikhiatr Im S S Korsakova Section Abstract Doc Link 19894294 Disease Relevance 1.38 Pain Relevance 0.26
Multi-day administration and comparison to fentanyl IV PCA
Gene_expression (fentanyl) of PCA associated with patient controlled alalgesia
11) Confidence 0.57 Published 2007 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1936285 Disease Relevance 0.09 Pain Relevance 0.33
While patient-controlled epidural analgesia (PCEA) offers many of the same benefits of IV PCA, patient preference study results indicated that patients prefer IV PCA to PCEA (Sinatra RS et al 2002).
Gene_expression (prefer) of PCA associated with patient controlled alalgesia and patient controlled epidural analgesia
12) Confidence 0.57 Published 2007 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1936285 Disease Relevance 0.50 Pain Relevance 2.52
The clinical character of Pca detected by mass screening is compared with control (i.e., Pca detected in the outpatient clinic in Gunma University).
Gene_expression (detected) of Pca associated with prostate cancer
13) Confidence 0.57 Published 1988 Journal Prostate Section Abstract Doc Link 3375142 Disease Relevance 0.93 Pain Relevance 0
The PCA conducted on the same 27 items to define an alternative structure for the EDSQ led to eight factors with eigenvalues greater than one, explaining 65% of the total variance.
Gene_expression (conducted) of PCA
14) Confidence 0.56 Published 2010 Journal BMC Ophthalmol Section Body Doc Link PMC2832632 Disease Relevance 0.06 Pain Relevance 0
RESULTS: LPS induced a significant expression of PCA at 6, 12, and 24 h, with a significantly increased production of 6-keto-PGF1 alpha, whereas the increased PGE2 production was much less pronounced.
Gene_expression (expression) of PCA
15) Confidence 0.53 Published 1995 Journal Scand. J. Gastroenterol. Section Body Doc Link 7701246 Disease Relevance 0 Pain Relevance 0
After incubation, supernatants were analysed for 6-keto-prostaglandin (PG) F1 alpha and PGE2 content, whereas cells were freeze-fractured and assayed in a one-stage clotting assay for the expression of procoagulant activity (PCA).
Gene_expression (expression) of PCA
16) Confidence 0.53 Published 1995 Journal Scand. J. Gastroenterol. Section Body Doc Link 7701246 Disease Relevance 0 Pain Relevance 0
The aims of this preliminary prospective observational study were to investigate the maternal side-effects and early neonatal effects, and to assess the placental transfer of remifentanil PCA during labour.
Gene_expression (transfer) of PCA associated with patient controlled alalgesia and ultiva
17) Confidence 0.51 Published 2005 Journal Br J Anaesth Section Abstract Doc Link 16113038 Disease Relevance 0 Pain Relevance 0.71
PCA may produce more appropriate and effective use of PCA.
Gene_expression (produce) of PCA
18) Confidence 0.51 Published 1994 Journal Br J Anaesth Section Abstract Doc Link 8198903 Disease Relevance 0.36 Pain Relevance 0.62
To help elucidate the basis for these results, the effect of these agents on production of PCA by another M phi population, the hepatic M phi (H-M phi PCA is functionally discrete from A-M phi PCA) was evaluated.
Gene_expression (production) of PCA
19) Confidence 0.51 Published 1986 Journal J. Surg. Res. Section Abstract Doc Link 3081762 Disease Relevance 0.52 Pain Relevance 0.29
The effect of pretreatment (T-10 min) of M phi cultures with the various inhibitors on PCA production at 8 hr post-LPS was evaluated, (N = 6 to 10 experiments).
Gene_expression (production) of PCA
20) Confidence 0.51 Published 1986 Journal J. Surg. Res. Section Abstract Doc Link 3081762 Disease Relevance 0.33 Pain Relevance 0.11

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