INT170556

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Context Info
Confidence 0.06
First Reported 2001
Last Reported 2001
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 12
Disease Relevance 17.85
Pain Relevance 1.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Narf) biological_process (Narf)
Anatomy Link Frequency
blood 3
14.2 1
Narf (Mus musculus)
Pain Link Frequency Relevance Heat
depression 24 100.00 Very High Very High Very High
anesthesia 240 99.56 Very High Very High Very High
ketamine 96 79.04 Quite High
alcohol 12 42.96 Quite Low
Disease Link Frequency Relevance Heat
Ocular Hypertension 2028 100.00 Very High Very High Very High
Depression 12 100.00 Very High Very High Very High
Congenital Anomalies 12 99.98 Very High Very High Very High
Sprains And Strains 1044 99.28 Very High Very High Very High
Obesity 204 97.04 Very High Very High Very High
Diabetes Mellitus 240 96.08 Very High Very High Very High
Hypopigmentation 48 91.04 High High
Glaucoma 204 86.24 High High
Unconsciousness 12 66.04 Quite High
Hypotension 24 64.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, in one experiment, B6 males had an average IOP of 14.2 ± 0.3 mmHg (n = 12) whereas the average IOP of females was 13.1 ± 0.3 mmHg (n = 12, P = 0.01).
Gene_expression (had) of IOP in 14.2 associated with ocular hypertension
1) Confidence 0.06 Published 2001 Journal BMC Genet Section Body Doc Link PMC48141 Disease Relevance 1.64 Pain Relevance 0.19
Average IOP for age matched mice of the same strain assessed at different times typically differed by no more than 1.5 mmHg, and the differences were usually smaller.
Gene_expression (matched) of IOP associated with sprains and strains and ocular hypertension
2) Confidence 0.06 Published 2001 Journal BMC Genet Section Body Doc Link PMC48141 Disease Relevance 2.06 Pain Relevance 0
Our comparison of the relationship between blood pressure and IOP in young, adult female mice of different mouse strains, whose blood pressures differed up to 36 mmHg, did not reveal a positive correlation.
Gene_expression (pressure) of IOP in blood associated with sprains and strains and ocular hypertension
3) Confidence 0.06 Published 2001 Journal BMC Genet Section Body Doc Link PMC48141 Disease Relevance 2.08 Pain Relevance 0
Intraocular pressure (IOP), C57BL/6J (B6), chromosome (Chr), polymerase chain reaction (PCR), carbonic anhydrase (CA)



Gene_expression (pressure) of IOP associated with ocular hypertension
4) Confidence 0.06 Published 2001 Journal BMC Genet Section Body Doc Link PMC48141 Disease Relevance 0.30 Pain Relevance 0
An initial study of the relationship between blood pressure and IOP in mice did not detect a good correlation (R2 = 0.1, Figure 7).


Gene_expression (pressure) of IOP in blood associated with ocular hypertension
5) Confidence 0.06 Published 2001 Journal BMC Genet Section Body Doc Link PMC48141 Disease Relevance 1.62 Pain Relevance 0.34
The increased IOP in A/J also was reproducible, with the average IOP of mice assessed in the year 2000 being 14.5 ± 0.4 mmHg (n = 16).
Gene_expression (reproducible) of IOP associated with ocular hypertension
6) Confidence 0.06 Published 2001 Journal BMC Genet Section Body Doc Link PMC48141 Disease Relevance 1.73 Pain Relevance 0
Further studies are needed to determine if blood pressure correlates with IOP in males, and to determine the relationship between blood pressure and IOP in various mouse strains with age.


Gene_expression (pressure) of IOP in blood associated with sprains and strains and ocular hypertension
7) Confidence 0.06 Published 2001 Journal BMC Genet Section Body Doc Link PMC48141 Disease Relevance 2.45 Pain Relevance 0
IOP was even lower in the 24 month B6 mice (10.8 ± 0.4 mmHg), and again the average IOP of young controls measured at the same time was not changed (13.5 ± 0.2, n = 12).
Gene_expression (lower) of IOP associated with ocular hypertension
8) Confidence 0.06 Published 2001 Journal BMC Genet Section Body Doc Link PMC48141 Disease Relevance 1.16 Pain Relevance 0
IOP was even lower in the 24 month B6 mice (10.8 ± 0.4 mmHg), and again the average IOP of young controls measured at the same time was not changed (13.5 ± 0.2, n = 12).
Neg (not) Gene_expression (changed) of IOP associated with ocular hypertension
9) Confidence 0.06 Published 2001 Journal BMC Genet Section Body Doc Link PMC48141 Disease Relevance 1.30 Pain Relevance 0
The IOP depression occurred very soon after anesthesia in the rats but was delayed in the mice.


Gene_expression (depression) of IOP associated with anesthesia, depression and ocular hypertension
10) Confidence 0.06 Published 2001 Journal BMC Genet Section Body Doc Link PMC48141 Disease Relevance 0.98 Pain Relevance 0.93
It is not known if these abnormalities affect mammalian IOP.
Gene_expression (affect) of IOP associated with congenital anomalies and ocular hypertension
11) Confidence 0.06 Published 2001 Journal BMC Genet Section Body Doc Link PMC48141 Disease Relevance 0.97 Pain Relevance 0
The mean IOP of groups analyzed at each time point did not differ (P = 0.9) indicating that the IOP depressing effect of anesthesia occurs later than 12 minutes after administration.
Gene_expression (depressing) of IOP associated with anesthesia and ocular hypertension
12) Confidence 0.06 Published 2001 Journal BMC Genet Section Body Doc Link PMC48141 Disease Relevance 1.56 Pain Relevance 0.50

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