INT17056

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Context Info
Confidence 0.57
First Reported 1983
Last Reported 2010
Negated 0
Speculated 3
Reported most in Body
Documents 37
Total Number 40
Disease Relevance 13.15
Pain Relevance 5.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (DLD) small molecule metabolic process (DLD) oxidoreductase activity (DLD)
aging (DLD) cellular nitrogen compound metabolic process (DLD) cytoplasm (DLD)
Anatomy Link Frequency
proximal 8
heart 2
myocardium 1
saphenous vein 1
telencephalic 1
DLD (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 16 100.00 Very High Very High Very High
Enkephalin 9 100.00 Very High Very High Very High
substance P 8 100.00 Very High Very High Very High
Calcitonin gene-related peptide 7 100.00 Very High Very High Very High
Neuropeptide 3 100.00 Very High Very High Very High
Serotonin 1 100.00 Very High Very High Very High
Opioid 12 99.66 Very High Very High Very High
Delta opioid receptors 2 98.52 Very High Very High Very High
adenocard 61 97.72 Very High Very High Very High
Inflammatory response 4 96.44 Very High Very High Very High
Disease Link Frequency Relevance Heat
Restenosis 33 100.00 Very High Very High Very High
Disease 64 99.92 Very High Very High Very High
Injury 133 99.86 Very High Very High Very High
Cv General 2 Under Development 16 99.84 Very High Very High Very High
Coronary Heart Disease 24 99.48 Very High Very High Very High
Myocardial Infarction 193 99.44 Very High Very High Very High
Tics 6 98.62 Very High Very High Very High
INFLAMMATION 30 96.04 Very High Very High Very High
Pathologic Constriction 152 95.96 Very High Very High Very High
Calcification 1 95.36 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The purpose of this study was to analyze normal and inflamed human dental pulp for the presence of NADPH-diaphorase (NADPH-d), as an index of NO system activity.
Spec (analyze) Gene_expression (presence) of NADPH-diaphorase in dental pulp
1) Confidence 0.57 Published 2008 Journal Micron Section Abstract Doc Link 18337111 Disease Relevance 0.43 Pain Relevance 0.34
LAD continuing as PDA across the left ventricular apex has been described once but only as a variation of single left coronary artery, in the absence of a right coronary ostium [35].
Gene_expression (continuing) of LAD in left coronary artery
2) Confidence 0.57 Published 2007 Journal J Cardiothorac Surg Section Body Doc Link PMC2104526 Disease Relevance 0.36 Pain Relevance 0
There was significant palpable disease in proximal and mid LAD as well as in its large diagonal (Dx) branch.
Gene_expression (proximal) of LAD in proximal associated with disease
3) Confidence 0.57 Published 2007 Journal J Cardiothorac Surg Section Body Doc Link PMC2104526 Disease Relevance 0.30 Pain Relevance 0
Twenty-one (5.2%) cases of myocardial bridging were located at the middle third of the left anterior descending coronary artery (LAD), one (0.25%) case was at the proximal third of the LAD, and one (0.25%) case was at the distal third of the LAD.
Gene_expression (third) of LAD in proximal
4) Confidence 0.52 Published 2008 Journal Int J Cardiovasc Imaging Section Body Doc Link 17929194 Disease Relevance 0.11 Pain Relevance 0
Twenty-one (5.2%) cases of myocardial bridging were located at the middle third of the left anterior descending coronary artery (LAD), one (0.25%) case was at the proximal third of the LAD, and one (0.25%) case was at the distal third of the LAD.
Gene_expression (third) of LAD in proximal
5) Confidence 0.52 Published 2008 Journal Int J Cardiovasc Imaging Section Body Doc Link 17929194 Disease Relevance 0.12 Pain Relevance 0
In the proximal LAD versus proximal LCX/RCA group, lesions were longer (16.89 ± 8.1 mm versus 14.68 ± 7.38 mm, p = 0.007) and had lower frequency of proximal segment tortuosity (p = 0.03).
Gene_expression (proximal) of LAD in proximal
6) Confidence 0.51 Published 2007 Journal BMC Cardiovasc Disord Section Body Doc Link PMC1831789 Disease Relevance 0.44 Pain Relevance 0.08
However, acute angiographic success rate was higher in patients with proximal LAD lesions.
Gene_expression (lesions) of LAD in proximal
7) Confidence 0.51 Published 2007 Journal BMC Cardiovasc Disord Section Body Doc Link PMC1831789 Disease Relevance 0.06 Pain Relevance 0
In the proximal LAD versus proximal LCX/RCA group, lesions were longer (16.89 ± 8.1 mm versus 14.68 ± 7.38 mm, p = 0.007) and had lower frequency of proximal segment tortuosity (p = 0.03).
Gene_expression (proximal) of LAD in proximal
8) Confidence 0.51 Published 2007 Journal BMC Cardiovasc Disord Section Body Doc Link PMC1831789 Disease Relevance 0.44 Pain Relevance 0.08
In-hospital events, which occurred only as non-Q wave MI in our cohort, were observed in 8 (2%) in the proximal LAD group, while only 1 patient in the proximal LCX/RCA and non-proximal LAD group (0.8% and 0.4% respectively) displayed such symptoms(P = NS).
Gene_expression (group) of LAD in proximal associated with myocardial infarction
9) Confidence 0.51 Published 2007 Journal BMC Cardiovasc Disord Section Body Doc Link PMC1831789 Disease Relevance 0.40 Pain Relevance 0
Even after adjusting for factors such as stents, particularly drug-eluting stents, which were used most frequently in the proximal LAD group, no statistical difference was detectible.
Gene_expression (group) of LAD in proximal
10) Confidence 0.51 Published 2007 Journal BMC Cardiovasc Disord Section Body Doc Link PMC1831789 Disease Relevance 0.34 Pain Relevance 0.03
Synthesis and preliminary biological activity of [D-Phe3]- or [alpha,beta-dehydro-Phe3]dermorphin tetrapeptides.
Gene_expression (Synthesis) of Phe3
11) Confidence 0.50 Published 1985 Journal Farmaco Sci Section Title Doc Link 4029390 Disease Relevance 0 Pain Relevance 0.19
The RCA originating as a branch from the midportion of the LAD is a very rare anomaly.
Gene_expression (midportion) of LAD
12) Confidence 0.49 Published 2010 Journal J Cardiothorac Surg Section Body Doc Link PMC2890517 Disease Relevance 0.29 Pain Relevance 0.06
In our patient RCA was stemming from the midportion of the LAD and had not congenital heart disease.
Gene_expression (midportion) of LAD in heart associated with coronary heart disease
13) Confidence 0.49 Published 2010 Journal J Cardiothorac Surg Section Body Doc Link PMC2890517 Disease Relevance 0.34 Pain Relevance 0.07
The RIMA and saphenous vein grafts were grafted on the LAD, obtuse marginatus (OM) and RCA, respectively.
Gene_expression (grafted) of LAD in saphenous vein
14) Confidence 0.48 Published 2007 Journal J Med Case Reports Section Body Doc Link PMC1884161 Disease Relevance 1.02 Pain Relevance 0.06
Coronary angiography demonstrated normal left main stem, occlusion of LAD just beyond the first septal and first diagonal (figs 1 and 2), and normally distributed and disease free circumflex and right coronary arteries.
Gene_expression (occlusion) of LAD in stem associated with disease
15) Confidence 0.47 Published 2006 Journal J Cardiothorac Surg Section Body Doc Link PMC1613243 Disease Relevance 0.98 Pain Relevance 0.08
During RCA grafting, the heart is displaced more, resulting in greater alteration of the normal geometry than during LAD grafting (3, 4).
Gene_expression (grafting) of LAD in heart
16) Confidence 0.45 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526513 Disease Relevance 0.05 Pain Relevance 0
From a modified apical 2-chamber view the CVFR was measured both in the RDP and the distal segment of LAD, and hyperaemic flow was obtained by venous infusion of adenosine (140 ?
Gene_expression (distal segment) of LAD in distal segment associated with adenocard
17) Confidence 0.41 Published 2007 Journal Cardiovasc Ultrasound Section Body Doc Link PMC2100043 Disease Relevance 0.43 Pain Relevance 0.05
Generally it is easier to explore the CFR in left coronary circulation (LAD) due to its topography [16-19], even non-invasively [48,53,54], avoiding time-consuming and the technical limitations concerning RCA circulation assessment.
Gene_expression (explore) of LAD
18) Confidence 0.36 Published 2007 Journal Cardiovasc Ultrasound Section Body Doc Link PMC2137923 Disease Relevance 0.20 Pain Relevance 0
In human with non-obstructive coronary disease, the vast majority of investigations refers to patients with others cardiopathies or even to normal subjects, or employing another techniques, or just focusing only LAD [16-19], limiting therefore the pertinent reasoning.
Gene_expression (focusing) of LAD associated with coronary heart disease
19) Confidence 0.32 Published 2007 Journal Cardiovasc Ultrasound Section Body Doc Link PMC2137923 Disease Relevance 0.56 Pain Relevance 0
Dermorphin (I) and [D-Ala2, Phe3, Gly4, Tyr5, Pro6]-beta c-EP (II) have been synthesized by the solid-phase method (beta c-EP, camel beta-endorphin).
Gene_expression (synthesized) of Phe3
20) Confidence 0.30 Published 1983 Journal Int. J. Pept. Protein Res. Section Abstract Doc Link 6853023 Disease Relevance 0 Pain Relevance 0.36

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