INT170600

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Context Info
Confidence 0.39
First Reported 2001
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 16
Total Number 16
Disease Relevance 1.29
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (RELA) nucleoplasm (RELA) aging (RELA)
nucleus (RELA) DNA binding (RELA) transcription factor binding (RELA)
RELA (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 45 83.32 Quite High
dexamethasone 15 70.52 Quite High
Inflammation 51 51.60 Quite High
cytokine 34 5.00 Very Low Very Low Very Low
Angina 30 5.00 Very Low Very Low Very Low
spastic colon 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperplasia 20 95.92 Very High Very High Very High
Obesity 1 89.44 High High
Stress 5 77.60 Quite High
Death 20 75.04 Quite High
Injury 60 71.68 Quite High
Adhesions 106 70.52 Quite High
Cancer 32 62.00 Quite High
Necrosis 32 61.52 Quite High
Apoptosis 11 53.76 Quite High
INFLAMMATION 51 51.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
No inhibitory effect was seen after selective addition of antisense RelA p65 and NF-?
Negative_regulation (selective) of Gene_expression (addition) of RelA
1) Confidence 0.39 Published 2001 Journal BMC Mol Biol Section Body Doc Link PMC48145 Disease Relevance 0.06 Pain Relevance 0
However the superiority of the combined therapy was demonstrated by the fact that the inhibitory potential was almost doubled after the simultaneous therapy with RelA p65 and NF-?
Negative_regulation (doubled) of Gene_expression (therapy) of RelA
2) Confidence 0.39 Published 2001 Journal BMC Mol Biol Section Body Doc Link PMC48145 Disease Relevance 0.07 Pain Relevance 0
The inhibition of ICAM-1 expression in HUVEC and HCAEC after simultaneous addition of antisense RelA p65 and NF-?
Negative_regulation (inhibition) of Gene_expression (addition) of RelA
3) Confidence 0.39 Published 2001 Journal BMC Mol Biol Section Body Doc Link PMC48145 Disease Relevance 0.07 Pain Relevance 0
M/mL and 74, 79, and 82% after incubation with antisense RelA p65 oligonucleotides in a concentration of 10, 20, and 30 ?
Negative_regulation (antisense) of Gene_expression (oligonucleotides) of RelA
4) Confidence 0.39 Published 2001 Journal BMC Mol Biol Section Body Doc Link PMC48145 Disease Relevance 0 Pain Relevance 0
The expression of ICAM-1 was 132, 129, and 113% after incubation with antisense p65 oligonucleotides in a concentration of 1, 2, and 4 ?
Negative_regulation (antisense) of Gene_expression (oligonucleotides) of p65
5) Confidence 0.39 Published 2001 Journal BMC Mol Biol Section Body Doc Link PMC48145 Disease Relevance 0 Pain Relevance 0
However the superiority of the combined therapy was demonstrated by the fact that the inhibitory potential was almost doubled after the simultaneous therapy with RelA p65 and NF-?
Negative_regulation (doubled) of Gene_expression (therapy) of p65
6) Confidence 0.39 Published 2001 Journal BMC Mol Biol Section Body Doc Link PMC48145 Disease Relevance 0.07 Pain Relevance 0
M/mL and 75, 89, 77% after incubation with antisense RelA p65 oligonucleotide in a concentration of 10, 20, and 30 ?
Negative_regulation (antisense) of Gene_expression (oligonucleotide) of p65
7) Confidence 0.39 Published 2001 Journal BMC Mol Biol Section Body Doc Link PMC48145 Disease Relevance 0 Pain Relevance 0
No inhibitory effect was seen after selective addition of antisense RelA p65 and NF-?
Negative_regulation (seen) of Gene_expression (addition) of RelA
8) Confidence 0.39 Published 2001 Journal BMC Mol Biol Section Body Doc Link PMC48145 Disease Relevance 0.06 Pain Relevance 0
M/mL and 74, 79, and 82% after incubation with antisense RelA p65 oligonucleotides in a concentration of 10, 20, and 30 ?
Negative_regulation (antisense) of Gene_expression (oligonucleotides) of p65
9) Confidence 0.39 Published 2001 Journal BMC Mol Biol Section Body Doc Link PMC48145 Disease Relevance 0 Pain Relevance 0
The inhibition of ICAM-1 expression in HUVEC and HCAEC after simultaneous addition of antisense RelA p65 and NF-?
Negative_regulation (inhibition) of Gene_expression (addition) of p65
10) Confidence 0.39 Published 2001 Journal BMC Mol Biol Section Body Doc Link PMC48145 Disease Relevance 0.07 Pain Relevance 0
No inhibitory effect was seen after selective addition of antisense RelA p65 and NF-?
Negative_regulation (seen) of Gene_expression (addition) of p65
11) Confidence 0.39 Published 2001 Journal BMC Mol Biol Section Body Doc Link PMC48145 Disease Relevance 0.06 Pain Relevance 0
M/mL and 75, 89, 77% after incubation with antisense RelA p65 oligonucleotide in a concentration of 10, 20, and 30 ?
Negative_regulation (antisense) of Gene_expression (oligonucleotide) of RelA
12) Confidence 0.39 Published 2001 Journal BMC Mol Biol Section Body Doc Link PMC48145 Disease Relevance 0 Pain Relevance 0
In the study presented we added antisense RelA p65 and NF-?
Negative_regulation (presented) of Gene_expression (antisense) of p65
13) Confidence 0.39 Published 2001 Journal BMC Mol Biol Section Body Doc Link PMC48145 Disease Relevance 0 Pain Relevance 0.11
No inhibitory effect was seen after selective addition of antisense RelA p65 and NF-?
Negative_regulation (selective) of Gene_expression (addition) of p65
14) Confidence 0.39 Published 2001 Journal BMC Mol Biol Section Body Doc Link PMC48145 Disease Relevance 0.06 Pain Relevance 0
In the study presented we added antisense RelA p65 and NF-?
Negative_regulation (presented) of Gene_expression (antisense) of RelA
15) Confidence 0.39 Published 2001 Journal BMC Mol Biol Section Body Doc Link PMC48145 Disease Relevance 0 Pain Relevance 0.11
After 1 h exposure to L. plantarum WCFS1, four major transcriptional regulators were all found to be downregulated: the oncogene product MYC (c-Myc), FOS (c-Fos), JUN (c-Jun) and the p65 subunit of the NF-?
Negative_regulation (downregulated) of Gene_expression (subunit) of p65
16) Confidence 0.19 Published 2008 Journal BMC Genomics Section Body Doc Link PMC2519092 Disease Relevance 0.78 Pain Relevance 0.03

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