INT170604

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.35
First Reported 2001
Last Reported 2010
Negated 2
Speculated 1
Reported most in Body
Documents 50
Total Number 51
Disease Relevance 12.71
Pain Relevance 4.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (GOPC) plasma membrane (GOPC) cytoplasm (GOPC)
Anatomy Link Frequency
nerves 4
bars 2
erythrocyte 2
plasma cells 2
anatomy 2
GOPC (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 72 100.00 Very High Very High Very High
rheumatoid arthritis 97 99.46 Very High Very High Very High
Potency 45 99.44 Very High Very High Very High
aspirin 30 99.20 Very High Very High Very High
Inflammation 305 98.70 Very High Very High Very High
drug abuse 58 98.36 Very High Very High Very High
potassium channel 44 96.40 Very High Very High Very High
qutenza 133 96.04 Very High Very High Very High
cINOD 62 94.80 High High
COX-2 inhibitor 9 93.88 High High
Disease Link Frequency Relevance Heat
Apoptosis 175 100.00 Very High Very High Very High
Obesity 82 100.00 Very High Very High Very High
Systemic Lupus Erythematosus 48 99.90 Very High Very High Very High
Metastasis 38 99.48 Very High Very High Very High
Rheumatoid Arthritis 99 99.46 Very High Very High Very High
Weight Loss 28 99.44 Very High Very High Very High
Emergencies 8 99.32 Very High Very High Very High
INFLAMMATION 355 98.70 Very High Very High Very High
Drug Dependence 59 98.36 Very High Very High Very High
Carcinoma 95 97.96 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fig. 3Mean peak contact pressures with one standard deviation
Negative_regulation (deviation) of Gene_expression (pressures) of Fig
1) Confidence 0.35 Published 2007 Journal Knee Surg Sports Traumatol Arthrosc Section Body Doc Link PMC2190783 Disease Relevance 0.24 Pain Relevance 0
The preservation of autonomic nerves was focused on the following three anatomic sites: (1) inferior mesenteric plexus (Fig. 1B); (2) superior hypogastric plexus (Fig. 1C); and (3) the paired hypogastric nerves (Fig. 1D).
Negative_regulation (paired) of Gene_expression (nerves) of Fig in nerves
2) Confidence 0.34 Published 2008 Journal Ann Surg Oncol Section Body Doc Link PMC2373867 Disease Relevance 0.49 Pain Relevance 0
The preservation of autonomic nerves was focused on the following three anatomic sites: (1) inferior mesenteric plexus (Fig. 1B); (2) superior hypogastric plexus (Fig. 1C); and (3) the paired hypogastric nerves (Fig. 1D).
Negative_regulation (paired) of Gene_expression (nerves) of Fig in nerves
3) Confidence 0.34 Published 2008 Journal Ann Surg Oncol Section Body Doc Link PMC2373867 Disease Relevance 0.50 Pain Relevance 0
As shown in Fig. 2, overall the rates of emergent referral to the regional hospital decreased steadily during the 3 years.Fig1Profile of the surgical emergencies treated in the three district hospitalsFig. 2Number of emergencies transferred from district hospitals to regional hospitals since the assignment of Capacity of District Surgery in district hospitals at the end of 2006

Elective surgeries

Negative_regulation (decreased) of Gene_expression (1Profile) of Fig associated with emergencies
4) Confidence 0.31 Published 2009 Journal World J Surg Section Body Doc Link PMC2746305 Disease Relevance 1.31 Pain Relevance 0
The concept {not both} does not reduce to the product of the
                   elementary concepts {probably not n1} and {probability not
                   n2}, Fig. 4B.
                   
Neg (not) Negative_regulation (reduce) of Gene_expression (product) of Fig
5) Confidence 0.27 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2713405 Disease Relevance 0 Pain Relevance 0
Degeneration may affect groups of primary (and secondary) follicles, as shown in Fig. 11A,11B,11C.
Negative_regulation (shown) of Gene_expression (11A) of Fig in follicles
6) Confidence 0.22 Published 2004 Journal Reprod Biol Endocrinol Section Body Doc Link PMC420494 Disease Relevance 0.09 Pain Relevance 0
Exposure to 10 nM ouabain for two days did not significantly change PPARG or LPL expression (Fig. 5A), but a four-day exposure resulted in a 2.5-fold decrease in PPARG and 3.7-fold decrease in LPL expression (Fig. 5B, p<0.02) compared to untreated AD.
Negative_regulation (decrease) of Gene_expression (expression) of Fig
7) Confidence 0.22 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2581599 Disease Relevance 0 Pain Relevance 0
On the other hand, cells expressing NUP98-HOXA9/N51S did not show morphologic evidence of erythroid immaturity in Giemsa-stained preparations (Fig. 8 and Table 1); yet a clear block in erythroid differentiation was observed by flow cytometry as evidenced by decreased expression of CD235a (Fig. 9A).
Negative_regulation (decreased) of Gene_expression (expression) of Fig
8) Confidence 0.21 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2725295 Disease Relevance 0.08 Pain Relevance 0
Fig2Radiological (a pre-RF ablation, b after RF ablation) and biochemical changes after RF ablation of the lung metastasis, demonstrating a severe drop in serum PTH concentrations, which persisted for almost a yearFig. 3Radiological and biochemical changes following lobectomy of the lung metastasis, which resulted in only partial improvement in serum calcium and PTH concentrations
Negative_regulation (ablation) of Gene_expression (2Radiological) of Fig in lung associated with metastasis
9) Confidence 0.20 Published 2010 Journal Horm Cancer Section Body Doc Link PMC3000473 Disease Relevance 1.00 Pain Relevance 0.03
Matured hMNPs displayed a mature, branched morphology (Fig. 1f), 97.7+/?
Negative_regulation (morphology) of Gene_expression (displayed) of Fig
10) Confidence 0.20 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912300 Disease Relevance 0 Pain Relevance 0
Conversely, the caspase-1 inhibitor YVAD was ineffective at inhibiting these processes (Fig. 6C), clearly indicating that, under the conditions studied, PS exposure is dissociated from IL-1?
Negative_regulation (inhibiting) of Gene_expression (processes) of Fig
11) Confidence 0.18 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2906308 Disease Relevance 0 Pain Relevance 0.09
The decreased expression of both message and protein in preterm tissues however (Fig. 3C, 4B) is consistent with our hypothesis.
Negative_regulation (decreased) of Gene_expression (expression) of Fig
12) Confidence 0.17 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2928262 Disease Relevance 0 Pain Relevance 0.12
The energy transfer between t-PnA and DOPE-NBD was minimally changed by Indo (Fig. 2B), possibly because the FRET efficiency between the probes was extremely low (?
Spec (possibly) Negative_regulation (low) of Gene_expression (changed) of Fig
13) Confidence 0.17 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2809093 Disease Relevance 0 Pain Relevance 0
Exposure to 10 nM ouabain for two days did not significantly change PPARG or LPL expression (Fig. 5A), but a four-day exposure resulted in a 2.5-fold decrease in PPARG and 3.7-fold decrease in LPL expression (Fig. 5B, p<0.02) compared to untreated AD.
Negative_regulation (decrease) of Gene_expression (expression) of Fig
14) Confidence 0.16 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2581599 Disease Relevance 0 Pain Relevance 0
In addition, as with AD differentiation, a four-day exposure to the treatments resulted in larger decreases in both ALP expression (3.8- and 9.2-fold for ouabain and K+, respectively, p<0.0001) and BSP expression by Day 7 (5.7-fold decrease for ouabain, p<0.0004, and undetectable levels for K+) (Fig. 9B, right).
Negative_regulation (decreases) of Gene_expression (expression) of Fig
15) Confidence 0.16 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2581599 Disease Relevance 0 Pain Relevance 0
Pre-treatment of Nuc with the anti-Nuc polyclonal antibody prevented the increase in PGE2 production (Fig. 6B), pointing to a specific implication of Nuc in this process.
Negative_regulation (prevented) of Gene_expression (production) of Fig
16) Confidence 0.16 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2373884 Disease Relevance 0 Pain Relevance 0.04
Pre-treatment of cells with CQ inhibited the down-regulation of p21Cip1 and p27Kip1 expression induced by 5-FU and, on the other hand, decreased the expression of CDK2 (Fig. 7).
Negative_regulation (decreased) of Gene_expression (expression) of Fig
17) Confidence 0.13 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2914703 Disease Relevance 0.21 Pain Relevance 0
g/ml) was incubated with unstimulated cartilage explants there is a reduction in IGF-1 production below control values (Fig. 5, P < 0.01).
Negative_regulation (reduction) of Gene_expression (production) of Fig in cartilage
18) Confidence 0.13 Published 2007 Journal J Inflamm (Lond) Section Body Doc Link PMC1971260 Disease Relevance 0.14 Pain Relevance 0.07
Calmodulin 2 (CALM2) expression (Fig. 3, blue bars) was decreased in two microarray CALM2 clones.
Negative_regulation (decreased) of Gene_expression (expression) of Fig in bars
19) Confidence 0.13 Published 2006 Journal PLoS ONE Section Body Doc Link PMC1762434 Disease Relevance 0.53 Pain Relevance 0.18
Treatment of Huh7 cells with a Raf I-kinase inhibitor neither altered Mcl-1 expression nor influenced sensitivity towards chemotherapeutic drug-induced apoptosis (Fig. 2A, and data not shown).
Neg (neither) Negative_regulation (inhibitor) of Gene_expression (expression) of Fig associated with apoptosis
20) Confidence 0.12 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1601962 Disease Relevance 1.15 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox