INT170736

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Context Info
Confidence 0.48
First Reported 2001
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.05
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

biological_process (Ccl27a)
Anatomy Link Frequency
B-cell 1
Ccl27a (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 5 100.00 Very High Very High Very High
Chronic pancreatitis 37 89.32 High High
Inflammatory response 3 82.56 Quite High
gABA 1 64.56 Quite High
fibrosis 9 57.76 Quite High
Inflammation 26 55.92 Quite High
Hippocampus 48 46.96 Quite Low
Kinase C 1 45.00 Quite Low
Bile 6 5.00 Very Low Very Low Very Low
Central nervous system 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sickle Cell Anemia 46 99.50 Very High Very High Very High
Epstein-barr Virus 1 99.24 Very High Very High Very High
Acute Chest Syndrome 35 96.16 Very High Very High Very High
Adult Respiratory Distress Syndrome 1 91.08 High High
Primary Sclerosing Cholangitis 30 90.72 High High
Pancreatitis 54 89.32 High High
Targeted Disruption 4 88.84 High High
INFLAMMATION 27 82.20 Quite High
Autoimmune Disease 3 73.28 Quite High
Disease 48 71.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Of the ten genes assayed, the expression changes for eight genes were confirmed with a change of 1.3-fold or greater: intracisternal-A particles (Iap), upstream transcription factor 1 (Usf1), potassium voltage-gated channel, subfamily Q, member 2 (Kcnq2), chemokine (C-C motif) ligand 19 (Ccl19), erythroid differentiation regulator (edr), caspase 9 (Casp9), chemokine (C-C motif) ligand 27 (Ccl27), complement and component 4 (C4).
Gene_expression (expression) of Ccl27 associated with chemokine
1) Confidence 0.48 Published 2005 Journal Genome Biol Section Body Doc Link PMC1175968 Disease Relevance 0.10 Pain Relevance 0.13
SCD patients have increased levels of the PMN chemokine IL-8 during VOC, suggesting that during crisis there is increased PMN recruitment [32].
Gene_expression (levels) of PMN chemokine IL-8 associated with sickle cell anemia and chemokine
2) Confidence 0.04 Published 2001 Journal Respir Res Section Body Doc Link PMC59517 Disease Relevance 1.17 Pain Relevance 0.05
Moreover, the expression of CXCL13 (BCA-1, B-cell attracting chemokine 1) and CXCR5 (BLR1, Burkitt lymphoma receptor-1) was examined, aiming at identifying further AIPC-specific tissue markers possibly related to the autoimmune pathogenesis of this disorder.
Spec (examined) Gene_expression (expression) of attracting chemokine 1 in B-cell associated with chemokine and epstein-barr virus
3) Confidence 0.03 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440515 Disease Relevance 0.78 Pain Relevance 0.29

General Comments

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