INT170737

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Context Info
Confidence 0.20
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 3.51
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Acsl1) endoplasmic reticulum (Acsl1) plasma membrane (Acsl1)
peroxisome (Acsl1) ligase activity (Acsl1) lipid metabolic process (Acsl1)
Anatomy Link Frequency
platelet 2
heart 1
Acsl1 (Mus musculus)
Pain Link Frequency Relevance Heat
Angina 10 85.52 High High
metalloproteinase 26 74.64 Quite High
cytokine 9 72.04 Quite High
Inflammation 22 54.32 Quite High
ischemia 32 50.00 Quite Low
antagonist 1 47.12 Quite Low
cva 11 5.00 Very Low Very Low Very Low
aspirin 5 5.00 Very Low Very Low Very Low
fibrosis 4 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acute Coronary Syndrome 123 100.00 Very High Very High Very High
Acute Chest Syndrome 35 100.00 Very High Very High Very High
Sickle Cell Anemia 46 99.52 Very High Very High Very High
Hypersensitivity 5 97.64 Very High Very High Very High
Coronary Artery Disease 36 96.92 Very High Very High Very High
Hyperhomocysteinemia 2 92.72 High High
Obesity 5 92.20 High High
Atherosclerosis 4 89.40 High High
Stable Angina Pectoris 10 85.52 High High
Increased Venous Pressure Under Development 10 84.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
and MMP-9 is closely related to ACS, which may be applied as a serology indicator in treatment of patients with coronary heart disease.
Localization (related) of ACS in heart associated with acute coronary syndrome and coronary artery disease
1) Confidence 0.20 Published 2010 Journal Clinical Medicine Insights. Cardiology Section Body Doc Link PMC2956475 Disease Relevance 0.70 Pain Relevance 0.38
Data were acquired on a FACS Calibur flowcytometer (BD, Franklin Lakes, New Jersey, USA) and were analyzed using CellQuest (BD, Franklin Lakes, New Jersey, USA) and FlowJo software (Tree Star, Ashland, Oregon, USA).


Localization (flowcytometer) of FACS
2) Confidence 0.10 Published 2008 Journal Respir Res Section Body Doc Link PMC2335107 Disease Relevance 0.36 Pain Relevance 0
Our data suggest a higher platelet secretion of SPARC in NSTE-ACS patients.
Localization (secretion) of NSTE-ACS in platelet associated with acute coronary syndrome
3) Confidence 0.08 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2954807 Disease Relevance 0.78 Pain Relevance 0
Reactive oxygen species may play an important role in the vascular dysfunction that is observed during ACS and VOC of SCD.
Localization (observed) of ACS associated with sickle cell anemia and acute chest syndrome
4) Confidence 0.08 Published 2001 Journal Respir Res Section Body Doc Link PMC59517 Disease Relevance 0.98 Pain Relevance 0
Interestingly, the levels of platelet-secreted glycoprotein SPARC were decreased in platelets from NSTE-ACS patients as compared to stable controls, which is consistent with a platelet secretion associated to platelet activation in NSTE-ACS.
Localization (decreased) of NSTE-ACS in platelets associated with acute coronary syndrome
5) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2954807 Disease Relevance 0.68 Pain Relevance 0

General Comments

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