INT170744

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Context Info
Confidence 0.20
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.30
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Edn1) extracellular region (Edn1) cell-cell signaling (Edn1)
cytoplasm (Edn1)
Edn1 (Mus musculus)
Pain Link Frequency Relevance Heat
Bioavailability 1 81.28 Quite High
cytokine 10 75.64 Quite High
Angina 2 28.72 Quite Low
cva 3 19.92 Low Low
ischemia 9 15.12 Low Low
Inflammation 14 7.44 Low Low
Pain score 1 6.12 Low Low
fibrosis 20 5.00 Very Low Very Low Very Low
Calcium channel 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sickle Cell Anemia 46 98.88 Very High Very High Very High
Infection 26 98.48 Very High Very High Very High
Acute Chest Syndrome 35 96.52 Very High Very High Very High
Increased Venous Pressure Under Development 5 93.12 High High
Thrombosis 5 92.80 High High
Muscular Spasm 3 92.20 High High
American Trypanosomiasis 32 88.88 High High
Toxicity 1 85.68 High High
Apoptosis 3 79.24 Quite High
Stress 7 72.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The consequences of T. cruzi infection of HUVECs with regard to the production of biologically active ET-1 are an increased expression of ET-1 mRNA [89].
Positive_regulation (increased) of Transcription (expression) of ET-1 associated with infection
1) Confidence 0.20 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2930857 Disease Relevance 0.78 Pain Relevance 0.06
Endothelin-1 transcription may be induced by activation of the redox-sensitive NF-?
Positive_regulation (induced) of Transcription (transcription) of Endothelin-1
2) Confidence 0.08 Published 2001 Journal Respir Res Section Body Doc Link PMC59517 Disease Relevance 0.52 Pain Relevance 0.04

General Comments

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