INT170754
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Moreover, CD8+ T-cells in the elderly display significantly decreased ability to secrete interferon-gamma (IFN-?) | |||||||||||||||
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In support of the postulated Th1 type response, intranasal immunization with H5N1 VLPs induced formation of memory T cells that could readily secrete IFN-? | |||||||||||||||
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However, TLR4pre inhibited the releases of IL-10 and IFN-? | |||||||||||||||
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Alternatively, effector T-cells of the Th1 subset activates macrophages by CD154 CD4+0 interactions and by secreting IFN-?. | |||||||||||||||
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B super-repressor in HEp2 tumors leads to significant increase in cytotoxicity and secretion of IFN-? | |||||||||||||||
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Lysis of hMSCs by untreated and IL-2 treated NK cells is inhibited by monocytes, however, the addition of monocytes induced significant secretion of IFN-? | |||||||||||||||
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Increased NK cell cytotoxicity and augmented secretion of IFN-? | |||||||||||||||
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Undifferentiated hMSCs were significantly more sensitive to lysis by IL-2 treated NK cells when compared to their differentiated counterparts (Fig. 5F), and triggered significant secretion of IFN-? | |||||||||||||||
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In ex vivo biopsy culture experiments, IL-15 is known to be induced by p3143, and it also drives secretion of IFN-? | |||||||||||||||
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Activated CD4+ T cells enact a Th1 response, secreting IFN-? | |||||||||||||||
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In addition, MSCs and their chondrocyte progeny alike inhibited the secretion of proinflammatory cytokines IFN-? | |||||||||||||||
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Untreated or anti-CD16 mAb treated NK cells did not secrete IFN-? | |||||||||||||||
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when co-cultured with any of the stem cell populations; however, both IL-2 treated and IL-2 in combination with anti-CD16 mAb treated NK cells in the presence and absence of stem cells secreted significant levels of IFN-? | |||||||||||||||
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Indeed, stem cells triggered significant secretion of IFN-? | |||||||||||||||
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Lysis of hESCs, hiPSCs, hDPSCs, and hMSCs by untreated and IL-2 treated NK cells is inhibited by anti-CD16 antibody treatment, however, the same treatment induced significant secretion of IFN-? | |||||||||||||||
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In vitro stimulation of splenocytes harvested from vaccinated mice with HBsAg resulted in a cytokine response characterized by significant secretion of hallmark Th1 type cytokines such as IFN-? | |||||||||||||||
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in co-cultures with hMSCs, and further synergized with IL-2 or IL-2 and anti-CD16 mAb treated NK samples to increase the release of IFN-? | |||||||||||||||
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As another means of measuring the T cell response elicited in the GM-CSF-adjuvanted and unadjuvanted vaccine groups, an ELISpot assay was used to enumerate the T cells in the blood of vaccinated animals secreting IFN-? | |||||||||||||||
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These cells release IFN-? | |||||||||||||||
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Phase 2 consists of recognition of bacterial antigens by CD4 lymphocytes, which release mainly IL-2 and IFN-? | |||||||||||||||
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