INT170756

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Context Info
Confidence 0.42
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.74
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

ATPase activity (Cftr) enzyme binding (Cftr) molecular_function (Cftr)
protein complex (Cftr) transmembrane transport (Cftr) cytoplasm (Cftr)
Cftr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 1 98.60 Very High Very High Very High
fibrosis 34 95.96 Very High Very High Very High
Chronic pancreatitis 2 51.40 Quite High
Bile 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 4 99.54 Very High Very High Very High
INFLAMMATION 1 98.60 Very High Very High Very High
Infection 1 98.04 Very High Very High Very High
Appetite Loss 2 97.48 Very High Very High Very High
Adenocarcinoma 3 97.16 Very High Very High Very High
Cystic Fibrosis 34 95.96 Very High Very High Very High
Malignant Neoplastic Disease 9 95.88 Very High Very High Very High
Digestive System Neoplasm 1 87.76 High High
Aspergillus Infection 2 56.28 Quite High
Sinusitis 4 54.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The key question is: are these neoplasms related to previously unrecognized functions of CFTR, or are they secondary to chronic inflammation, infection, or malnutrition, which might predispose to malignancy?
Negative_regulation (unrecognized) of Localization (functions) of CFTR associated with appetite loss, malignant neoplastic disease, inflammation, cancer and infection
1) Confidence 0.42 Published 2000 Journal Respir Res Section Body Doc Link PMC59552 Disease Relevance 1.74 Pain Relevance 0.31

General Comments

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