INT1708

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Context Info
Confidence 0.78
First Reported 1979
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 56
Total Number 56
Disease Relevance 6.92
Pain Relevance 10.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (OXTR) signal transducer activity (OXTR)
Anatomy Link Frequency
placenta 4
myometrium 3
plasma 3
uterus 3
umbilical artery 2
OXTR (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuropeptide 27 100.00 Very High Very High Very High
Enkephalin 10 100.00 Very High Very High Very High
Cholecystokinin 9 100.00 Very High Very High Very High
Nerve growth factor 1 100.00 Very High Very High Very High
antagonist 23 99.96 Very High Very High Very High
Somatostatin 5 99.96 Very High Very High Very High
Morphine 45 99.42 Very High Very High Very High
Calcitonin gene-related peptide 1 99.40 Very High Very High Very High
analgesia 20 99.28 Very High Very High Very High
addiction 8 99.18 Very High Very High Very High
Disease Link Frequency Relevance Heat
Natriuresis 3 98.96 Very High Very High Very High
Autism 18 98.40 Very High Very High Very High
Hemorrhage 96 98.36 Very High Very High Very High
Lumbar Puncture Related Headaches 1 98.12 Very High Very High Very High
Anxiety Disorder 67 97.28 Very High Very High Very High
Pre-term Labor 98 96.64 Very High Very High Very High
Cognitive Disorder 20 95.64 Very High Very High Very High
Respiratory Distress 2 94.04 High High
Dysmenorrhea 31 92.52 High High
Premature Birth 576 91.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, in the present study we investigated in the nonpregnant myometrium if oxytocin receptor expression can be affected by 17-beta-estradiol and oxytocin stimulation.
Gene_expression (expression) of oxytocin in myometrium
1) Confidence 0.78 Published 2003 Journal Arch. Gynecol. Obstet. Section Abstract Doc Link 14605818 Disease Relevance 0.08 Pain Relevance 0.13
CONCLUSIONS: Taken together, our data demonstrate that the dynamics of oxytocin receptor expression can be affected by stimulation with 17-beta-estradiol and oxytocin not only in the pregnant uterus, but also in the nonpregnant uterus.
Gene_expression (expression) of oxytocin in uterus
2) Confidence 0.78 Published 2003 Journal Arch. Gynecol. Obstet. Section Body Doc Link 14605818 Disease Relevance 0 Pain Relevance 0
The expression of the myometrial oxytocin receptor in both groups was compared immunohistochemically.
Gene_expression (expression) of oxytocin
3) Confidence 0.78 Published 2003 Journal Arch. Gynecol. Obstet. Section Body Doc Link 14605818 Disease Relevance 0 Pain Relevance 0
From the results presented it is concluded that the human fetus can be an important source of oxytocin and that neurohumoral birth reflexes described in animals do not occur systematically in man.
Gene_expression (source) of oxytocin
4) Confidence 0.78 Published 1985 Journal J Perinat Med Section Abstract Doc Link 3891956 Disease Relevance 0 Pain Relevance 0.20
This applies to the oxytocin production in the first and second stage of labour.
Gene_expression (production) of oxytocin
5) Confidence 0.78 Published 1998 Journal Clin. Sci. Section Abstract Doc Link 9662490 Disease Relevance 0.06 Pain Relevance 0.61
Effects of morphine administration on the fetal production of oxytocin in labour.
Gene_expression (production) of oxytocin associated with morphine
6) Confidence 0.78 Published 1998 Journal Clin. Sci. Section Title Doc Link 9662490 Disease Relevance 0.06 Pain Relevance 0.81
The results do not support transfer of oxytocin across the placenta in women.
Gene_expression (transfer) of oxytocin in placenta
7) Confidence 0.78 Published 1999 Journal Br J Obstet Gynaecol Section Abstract Doc Link 10609728 Disease Relevance 0 Pain Relevance 0.08
The results demonstrate that fetal production of oxytocin is not influenced by general anaesthesia, thus enabling comparison of labour and nonlabour samples at caesarean section.
Gene_expression (production) of oxytocin
8) Confidence 0.78 Published 1999 Journal Br J Obstet Gynaecol Section Abstract Doc Link 10609728 Disease Relevance 0 Pain Relevance 0.09
It is not known whether human labour is associated with increased fetal oxytocin production or transfer of oxytocin across the placenta.
Gene_expression (production) of oxytocin in placenta
9) Confidence 0.78 Published 1999 Journal Br J Obstet Gynaecol Section Abstract Doc Link 10609728 Disease Relevance 0 Pain Relevance 0.09
Previous workers have described the fetal production of oxytocin in addition to maternal production.
Gene_expression (production) of oxytocin
10) Confidence 0.78 Published 1998 Journal Clin. Sci. Section Abstract Doc Link 9662490 Disease Relevance 0 Pain Relevance 0.63
This study was designed to investigate the effect of an opiate (5 mg of morphine) given to the mother on the fetal production of oxytocin in labour. 2.
Gene_expression (production) of oxytocin associated with opiate and morphine
11) Confidence 0.78 Published 1998 Journal Clin. Sci. Section Abstract Doc Link 9662490 Disease Relevance 0.07 Pain Relevance 0.88
They regulate formation of gap junctions, influx of calcium ions, synthesis of oxytocin, adrenergic receptors and of prostaglandins and cyclic nucleotides.
Gene_expression (synthesis) of oxytocin
12) Confidence 0.78 Published 1991 Journal Ann. Acad. Med. Singap. Section Abstract Doc Link 2029168 Disease Relevance 0.31 Pain Relevance 0.35
A highly specific tritium labeled oxytocin (3H-OT) was synthesized utilizing the method of catalytic substitution of halogen for hydrogen.
Gene_expression (synthesized) of oxytocin
13) Confidence 0.78 Published 1979 Journal Endocrinol. Jpn. Section Abstract Doc Link 227664 Disease Relevance 0 Pain Relevance 0
Fetal oxytocin production was not affected by the maternal administration of morphine in the first stage of labour.
Gene_expression (production) of oxytocin associated with morphine
14) Confidence 0.68 Published 1998 Journal Clin. Sci. Section Abstract Doc Link 9662490 Disease Relevance 0.07 Pain Relevance 0.69
It is not known whether human labour is associated with increased fetal oxytocin production or transfer of oxytocin across the placenta.
Gene_expression (production) of oxytocin in placenta
15) Confidence 0.68 Published 1999 Journal Br J Obstet Gynaecol Section Abstract Doc Link 10609728 Disease Relevance 0 Pain Relevance 0.09
Labour was not associated with an increase in fetal oxytocin production.
Gene_expression (production) of oxytocin
16) Confidence 0.68 Published 1999 Journal Br J Obstet Gynaecol Section Abstract Doc Link 10609728 Disease Relevance 0 Pain Relevance 0.08
However, little is known about the mutual dependence of the oxytocin receptor, oxytocin and 17-beta-estradiol in the nonpregnant myometrium and about the distribution of the oxytocin receptor in the nonpregnant uterus.
Gene_expression (distribution) of oxytocin in myometrium associated with addiction
17) Confidence 0.67 Published 2003 Journal Arch. Gynecol. Obstet. Section Abstract Doc Link 14605818 Disease Relevance 0.09 Pain Relevance 0.14
However, little is known about the mutual dependence of the oxytocin receptor, oxytocin and 17-beta-estradiol in the nonpregnant myometrium and about the distribution of the oxytocin receptor in the nonpregnant uterus.
Gene_expression (distribution) of oxytocin in myometrium associated with addiction
18) Confidence 0.67 Published 2003 Journal Arch. Gynecol. Obstet. Section Abstract Doc Link 14605818 Disease Relevance 0.09 Pain Relevance 0.14
Oxytocin was also measured in the umbilical artery and vein during maternal oxytocin infusion to assess placental transfer.
Gene_expression (measured) of Oxytocin in vein
19) Confidence 0.67 Published 1999 Journal Br J Obstet Gynaecol Section Abstract Doc Link 10609728 Disease Relevance 0 Pain Relevance 0.08
Recent evidence suggests that oxytocin is most important for the initial phase of labour, whereas increased synthesis of PGF2 alpha is essential for the progression of labour.
Gene_expression (synthesis) of oxytocin
20) Confidence 0.67 Published 1984 Journal Br J Obstet Gynaecol Section Abstract Doc Link 6091729 Disease Relevance 0.07 Pain Relevance 0.07

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