INT17081

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Context Info
Confidence 0.27
First Reported 1990
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 2.12
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ttpa) intracellular (Ttpa) cytoplasm (Ttpa)
Anatomy Link Frequency
erythrocyte 2
plasma 1
Ttpa (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 3 98.98 Very High Very High Very High
alcohol 3 55.44 Quite High
Pain 6 10.00 Low Low
iatrogenic 1 7.68 Low Low
antagonist 10 5.00 Very Low Very Low Very Low
Central nervous system 9 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
Catecholamine 2 5.00 Very Low Very Low Very Low
endometriosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 5 99.76 Very High Very High Very High
Muscle Disease 3 99.22 Very High Very High Very High
Reprotox - General 3 16 86.32 High High
Obesity 3 76.00 Quite High
Hemolytic Uremic Syndrome 9 70.92 Quite High
Thrombotic Thrombocytopenic Purpura 6 69.52 Quite High
Reprotox - General 1 5 61.04 Quite High
Congenital Anomalies 4 42.56 Quite Low
Hypospadias 1 24.88 Low Low
Spina Bifida 1 20.40 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In plasma, alpha-tocopherol is found in all lipoprotein fractions but mostly is associated with apo B-containing lipoproteins. alpha-Tocopherol is associated with very-low-density lipoprotein when it is secreted from the liver.
alpha-tocopherol Binding (found) of in plasma
1) Confidence 0.27 Published 1990 Journal J. Nutr. Section Abstract Doc Link 2181082 Disease Relevance 0.27 Pain Relevance 0.12
In humans vitamin E is the most important lipid soluble antioxidant and deficiency may cause neurological dysfunction, myopathies and diminished erythrocyte life span. alpha-Tocopherol is absorbed via the lymphatic pathway and transported in association with chylomicrons.
alpha-Tocopherol Binding (association) of in erythrocyte associated with anesthesia, muscle disease and disorder of lipid metabolism
2) Confidence 0.27 Published 1990 Journal J. Nutr. Section Abstract Doc Link 2181082 Disease Relevance 0.27 Pain Relevance 0.12
Fourteen (11%) had taken quinine, and 7 had taken other drugs associated with TTP-HUS.
TTP-HUS Binding (associated) of
3) Confidence 0.20 Published 2001 Journal Ann. Intern. Med. Section Body Doc Link 11747383 Disease Relevance 0.21 Pain Relevance 0
Neurologic abnormalities were as severe in patients with quinine-associated TTP-HUS as in the 118 patients who had not taken quinine.
TTP-HUS Binding (quinine-associated) of
4) Confidence 0.18 Published 2001 Journal Ann. Intern. Med. Section Body Doc Link 11747383 Disease Relevance 0.20 Pain Relevance 0
Neurologic abnormalities were as severe in patients with quinine-associated TTP-HUS as in the 118 patients who had not taken quinine.
TTP-HUS Binding (quinine-associated) of
5) Confidence 0.18 Published 2001 Journal Ann. Intern. Med. Section Body Doc Link 11747383 Disease Relevance 0.20 Pain Relevance 0
Deficiency of vitamin E may cause neurological dysfunction, myopathies and diminished erythrocyte life span. alpha-Tocopherol is absorbed via the lymphatic pathway and transported in association with chylomicrons.
alpha-Tocopherol Binding (association) of in erythrocyte associated with anesthesia, muscle disease and disorder of lipid metabolism
6) Confidence 0.08 Published 1991 Journal Free Radic. Res. Commun. Section Abstract Doc Link 1874454 Disease Relevance 0.36 Pain Relevance 0.10
No consistent pattern of associations was observed by Curtis et al. in Canada, but some specific pesticides were tentatively associated with prolonged TTP [135].
TTP Binding (associated) of
7) Confidence 0.07 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1524969 Disease Relevance 0.61 Pain Relevance 0

General Comments

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