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Context Info
Confidence 0.44
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.93
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (RASGRP1) Golgi apparatus (RASGRP1) endoplasmic reticulum (RASGRP1)
cytoplasm (RASGRP1) cytosol (RASGRP1) lipid binding (RASGRP1)
Anatomy Link Frequency
liver 1
vesicles 1
RASGRP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
ischemia 13 93.92 High High
agonist 30 91.44 High High
Neurotransmitter 30 90.00 High High
Catecholamine 9 89.32 High High
Neuropeptide 238 78.48 Quite High
beta blocker 3 40.16 Quite Low
Angina 2 10.16 Low Low
Enkephalin 54 5.00 Very Low Very Low Very Low
Inflammation 18 5.00 Very Low Very Low Very Low
bradykinin 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 14 100.00 Very High Very High Very High
Cardiovascular Disease 2 100.00 Very High Very High Very High
Myocardial Infarction 35 99.00 Very High Very High Very High
Infarction 21 98.44 Very High Very High Very High
Cv Unclassified Under Development 12 93.92 High High
Necrosis 1 92.88 High High
Coronary Heart Disease 6 90.48 High High
Death 2 87.92 High High
Sepsis 44 86.60 High High
Obesity 16 85.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There was no relationship between serum creatinine and either measure of RAS activation.
Localization (measure) of RAS
1) Confidence 0.44 Published 2010 Journal Crit Care Section Body Doc Link PMC2875539 Disease Relevance 0.49 Pain Relevance 0.03
The RAS in cardiovascular disease
Localization (disease) of RAS associated with cardiovascular disease
2) Confidence 0.28 Published 2001 Journal Curr Control Trials Cardiovasc Med Section Body Doc Link PMC59642 Disease Relevance 1.08 Pain Relevance 0.05
LPL activity is mostly regulated posttranslationally via altered secretion from liver of LPL-modulating factors, including apolipoprotein C-III (Apoc3), apolipoprotein A-V (Apoa5), Angiopoietin-like protein 3 (Angptl3), and Angiopoietin-like protein 4 (Angptl4).
Localization (secretion) of A-V in liver associated with disorder of lipid metabolism
3) Confidence 0.03 Published 2010 Journal PPAR Research Section Body Doc Link PMC2948931 Disease Relevance 0.37 Pain Relevance 0.20
Interestingly, these secretory vesicles contained an extensive number of GTP nucleotide-binding proteins related to Rab, Rho, and Ras signaling molecules (50,51), together with SNARE-related proteins and annexins that are involved in trafficking and exocytosis of secretory vesicle components (52,53).
Localization (related) of Ras in vesicles
4) Confidence 0.01 Published 2010 Journal AAPS J Section Body Doc Link PMC2976990 Disease Relevance 0 Pain Relevance 0.74

General Comments

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