INT170823

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Context Info
Confidence 0.58
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.35
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

hydrolase activity, acting on glycosyl bonds (Gba2) plasma membrane (Gba2) lipid metabolic process (Gba2)
Anatomy Link Frequency
bile 1
Gba2 (Mus musculus)
Pain Link Frequency Relevance Heat
Bile 53 100.00 Very High Very High Very High
sodium channel 6 72.16 Quite High
fibrosis 30 55.08 Quite High
anesthesia 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 9 98.04 Very High Very High Very High
Cystic Fibrosis 30 55.08 Quite High
Disease 2 5.00 Very Low Very Low Very Low
Liver Disease 2 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low
Lower Respiratory Tract Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In summary, in the widely studied cftr knockout mouse model (which clearly demonstrates intestinal pathology), the apical sodium dependent ileal bile acid transporter is expressed and functions at higher levels than in wild-type animals, with intermediate levels of IBAT expression and function in heterozygous cftr (+/-) mice.
Gene_expression (expressed) of bile acid in bile associated with targeted disruption and bile
1) Confidence 0.58 Published 2001 Journal BMC Gastroenterol Section Body Doc Link PMC59644 Disease Relevance 0.35 Pain Relevance 0.29

General Comments

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